{"id":"ferric-citrate-1-gm-oral-tablet-auryxia","safety":{"commonSideEffects":[{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Abdominal discomfort"},{"rate":null,"effect":"Discolored feces"}]},"_chembl":{"chemblId":"CHEMBL3301597","moleculeType":"Small molecule","molecularWeight":"262.96"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Ferric citrate is an iron-based phosphate binder that forms insoluble complexes with dietary phosphate in the GI lumen, preventing phosphate absorption and reducing serum phosphate concentrations. This mechanism helps manage hyperphosphatemia in chronic kidney disease patients while simultaneously providing supplemental iron, which can help address iron deficiency anemia common in this population.","oneSentence":"Ferric citrate binds phosphate in the gastrointestinal tract to reduce serum phosphate levels in patients with chronic kidney disease.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:12:24.457Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hyperphosphatemia in patients with chronic kidney disease on dialysis"},{"name":"Iron deficiency anemia in patients with chronic kidney disease"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Auryxia"],"phase":"phase_3","status":"active","brandName":"Ferric Citrate 1 GM Oral Tablet [AURYXIA]","genericName":"Ferric Citrate 1 GM Oral Tablet [AURYXIA]","companyName":"USRC Kidney Research","companyId":"usrc-kidney-research","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ferric citrate binds phosphate in the gastrointestinal tract to reduce serum phosphate levels in patients with chronic kidney disease. Used for Hyperphosphatemia in patients with chronic kidney disease on dialysis, Iron deficiency anemia in patients with chronic kidney disease.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}