{"id":"fentonium","rwe":[{"pmid":"3531034","year":"1986","title":"A double-blind trial of fentonium bromide in the treatment of incontinent unstable bladder.","finding":"","journal":"International journal of clinical pharmacology, therapy, and toxicology","studyType":"Clinical Study"},{"pmid":"7209100","year":"1981","title":"[Clinico-endoscopic study of the comparative therapeutic effectiveness of cimetidine alone or combined with fentonium bromide in gastric and duodenal ulcer].","finding":"","journal":"Revista espanola de las enfermedades del aparato digestivo","studyType":"Clinical Study"},{"pmid":"740267","year":"1978","title":"[Effect of the combination of chenodeoxycholic acid and fentonium on the dynamics of the principal biliary tract in cholecystectomized subjects].","finding":"","journal":"Minerva dietologica e gastroenterologica","studyType":"Clinical Study"},{"pmid":"19285","year":"1977","title":"Inhibitory effect of fentonium on gastric acid secretion in different laboratory animals.","finding":"","journal":"Il Farmaco; edizione scientifica","studyType":"Clinical Study"},{"pmid":"332188","year":"1977","title":"Controlled double-blind trial on the clinical effects of the chenodeoxycholic acid-fentonium bromide combination in the symptomatic treatment of biliary spastic-dyskinetic conditions.","finding":"","journal":"Arzneimittel-Forschung","studyType":"Clinical Study"}],"tags":[{"label":"fentonium","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A03BB04","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"phentonium","offLabel":[],"synonyms":["fentonium","fentonium bromide","phenthonium","phenthonium bromide","phentonium","phentonium bromide"],"timeline":[],"approvals":[],"brandName":"Phentonium","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"fentonium","explanation":"Imagine your body's cells have locks on them, and Fentonium is a key that fits into one of those locks. When it binds to the lock, it can either open the lock to allow something in or out, or it can block the lock to prevent something from getting in or out. This can affect how the cell works and responds to signals.","oneSentence":"Fentonium is thought to work by interacting with a specific molecular target, although the exact nature of this interaction is not well understood.","technicalDetail":"Fentonium is a small molecule that binds to a specific protein target, potentially modulating its activity and influencing downstream signaling pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1167","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FENTONIUM","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:26:01.524095","biosimilars":[],"competitors":[{"drugName":"methscopolamine","drugSlug":"methscopolamine","fdaApproval":"1953-04-09","genericCount":5,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"methylhomatropine","drugSlug":"methylhomatropine","fdaApproval":"1943-03-23","relationship":"same-class"}],"genericName":"fentonium","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"methscopolamine","brandName":"methscopolamine","genericName":"methscopolamine","approvalYear":"1953","relationship":"same-class"},{"drugId":"methylhomatropine","brandName":"methylhomatropine","genericName":"methylhomatropine","approvalYear":"1943","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"26BF4S8FO5","CHEBI":"CHEBI:135781","INN_ID":"3384","UMLSCUI":"C0060206","ChEMBL_ID":"CHEMBL3989849","KEGG_DRUG":"D07951","DRUGBANK_ID":"DB08978","PUBCHEM_CID":"10347880","SECONDARY_CAS_RN":"34786-74-8","MESH_SUPPLEMENTAL_RECORD_UI":"C100112"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":8,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"A03BB04","allCodes":["A03BB04"]},"biosimilarFilings":[],"recentPublications":[{"date":"1986 Aug","pmid":"3531034","title":"A double-blind trial of fentonium bromide in the treatment of incontinent unstable bladder.","journal":"International journal of clinical pharmacology, therapy, and toxicology"},{"date":"1981 Jan","pmid":"7209100","title":"[Clinico-endoscopic study of the comparative therapeutic effectiveness of cimetidine alone or combined with fentonium bromide in gastric and duodenal ulcer].","journal":"Revista espanola de las enfermedades del aparato digestivo"},{"date":"1978 Jan-Mar","pmid":"740267","title":"[Effect of the combination of chenodeoxycholic acid and fentonium on the dynamics of the principal biliary tract in cholecystectomized subjects].","journal":"Minerva dietologica e gastroenterologica"},{"date":"1977 Jul","pmid":"19285","title":"Inhibitory effect of fentonium on gastric acid secretion in different laboratory animals.","journal":"Il Farmaco; edizione scientifica"},{"date":"1977","pmid":"332188","title":"Controlled double-blind trial on the clinical effects of the chenodeoxycholic acid-fentonium bromide combination in the symptomatic treatment of biliary spastic-dyskinetic conditions.","journal":"Arzneimittel-Forschung"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Fentonium, also known as Phentonium, is a small molecule drug of the fentonium class. Its exact target and mechanism of action are unknown, and it has not been approved by the FDA for any indications. The commercial status of Fentonium is unclear, with no information available on its patent status, generic manufacturers, or off-patent status. Further research is needed to understand the properties and potential uses of Fentonium. As a result, there is limited information available on its safety profile and pharmacokinetic properties.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}