{"id":"fenticlor","rwe":[{"pmid":"41850441","year":"2026","title":"Halogenated phenolic disinfectants suppress 11β-hydroxysteroid dehydrogenase 2 activity in human and rat models: Experimental and computational evidence.","finding":"","journal":"The Journal of steroid biochemistry and molecular biology","studyType":"Clinical Study"},{"pmid":"40784118","year":"2025","title":"Structure-activity relationships of halogenated disinfectants as potent inhibitors of 5α-reductase type 1: Potential impact on neurosteroid synthesis.","finding":"","journal":"Journal of hazardous materials","studyType":"Clinical Study"},{"pmid":"38058230","year":"2024","title":"Modified ESR-based photosafety test (ESR-PT) detecting singlet oxygen and free radical formation.","finding":"","journal":"Journal of applied toxicology : JAT","studyType":"Clinical Study"},{"pmid":"36450494","year":"2022","title":"False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine.","finding":"","journal":"The Journal of toxicological sciences","studyType":"Clinical Study"},{"pmid":"18991702","year":"2008","title":"Allergic and photoallergic contact dermatitis from ketoprofen: evaluation of cross-reactivities by a combination of photopatch testing and computerized conformational analysis.","finding":"","journal":"Current pharmaceutical design","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"meflorin","offLabel":[],"synonyms":["fenticlor","fentichlor","meflorin"],"timeline":[],"approvals":[],"brandName":"Meflorin","ecosystem":[],"mechanism":{"target":"Uracil-DNA glycosylase","modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and Meflorin is a key that fits into those locks. When Meflorin binds to its target, it helps to regulate the activity of the cells, which can help to treat certain conditions. This is a simplified explanation, and the actual mechanism may be more complex.","oneSentence":"Meflorin works by interacting with a specific biological target to produce a therapeutic effect.","technicalDetail":"The technical details of Meflorin's mechanism of action are not available, but it is classified as a small molecule drug, which means it is a small molecule with a molecular weight typically less than 900 Da."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3227","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FENTICLOR","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T13:44:22.777583","biosimilars":[],"competitors":[],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"fenticlor","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"UNII":"D61659OVD0","CHEBI":"CHEBI:556580","INN_ID":"2830","UMLSCUI":"C0060202","ChEMBL_ID":"CHEMBL473535","KEGG_DRUG":"D04164","PUBCHEM_CID":"7329","SNOMEDCT_US":"256223005","MESH_SUPPLEMENTAL_RECORD_UI":"C007713"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":17,"therapeuticAreas":["Metabolic"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar 16","pmid":"41850441","title":"Halogenated phenolic disinfectants suppress 11β-hydroxysteroid dehydrogenase 2 activity in human and rat models: Experimental and computational evidence.","journal":"The Journal of steroid biochemistry and molecular biology"},{"date":"2025 Sep 15","pmid":"40784118","title":"Structure-activity relationships of halogenated disinfectants as potent inhibitors of 5α-reductase type 1: Potential impact on neurosteroid synthesis.","journal":"Journal of hazardous materials"},{"date":"2024 Apr","pmid":"38058230","title":"Modified ESR-based photosafety test (ESR-PT) detecting singlet oxygen and free radical formation.","journal":"Journal of applied toxicology : JAT"},{"date":"2022","pmid":"36450494","title":"False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine.","journal":"The Journal of toxicological sciences"},{"date":"2008","pmid":"18991702","title":"Allergic and photoallergic contact dermatitis from ketoprofen: evaluation of cross-reactivities by a combination of photopatch testing and computerized conformational analysis.","journal":"Current pharmaceutical design"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Meflorin, also known as Fenticlor, is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it is not known if it is FDA approved or off-patent. The approved indications for Meflorin are also unknown. Further information on its pharmacokinetics, such as half-life and bioavailability, is not available. As a result, key safety considerations and generic manufacturers are also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}