{"id":"fentanyl-ethypharm","safety":{"commonSideEffects":[{"rate":null,"effect":"Respiratory depression"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Sedation"},{"rate":null,"effect":"Dependence/addiction risk"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Fentanyl acts as a potent mu-opioid receptor agonist, activating inhibitory pathways in the spinal cord and brain that reduce pain signal transmission and perception. The Ethypharm formulation is a pharmaceutical development of this well-established opioid, likely designed to optimize delivery, bioavailability, or safety profile compared to existing fentanyl products.","oneSentence":"Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:12:26.152Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Moderate to severe pain (acute or chronic)"},{"name":"Cancer pain"}]},"trialDetails":[{"nctId":"NCT01842893","phase":"PHASE3","title":"Efficacy and Safety of Fentanyl ETHYPHARM for Breakthrough Pain in Opioid-treated Patients With Cancer","status":"COMPLETED","sponsor":"Ethypharm","startDate":"2011-11","conditions":"Breakthrough Pain, Cancer","enrollment":91}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Fentanyl Ethypharm","genericName":"Fentanyl Ethypharm","companyName":"Ethypharm","companyId":"ethypharm","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation. Used for Moderate to severe pain (acute or chronic), Cancer pain.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}