{"id":"fenozolone","rwe":[{"pmid":"15950492","year":"2005","title":"Modulation of behavior and cortical motor activity in healthy subjects by a chronic administration of a serotonin enhancer.","finding":"","journal":"NeuroImage","studyType":"Clinical Study"},{"pmid":"11771971","year":"2002","title":"A single dose of the serotonin neurotransmission agonist paroxetine enhances motor output: double-blind, placebo-controlled, fMRI study in healthy subjects.","finding":"","journal":"NeuroImage","studyType":"Clinical Study"},{"pmid":"10598941","year":"1999","title":"Cerebral functional magnetic resonance imaging activation modulated by a single dose of the monoamine neurotransmission enhancers fluoxetine and fenozolone during hand sensorimotor tasks.","finding":"","journal":"Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism","studyType":"Clinical Study"},{"pmid":"9220042","year":"1997","title":"Abuse of prescription medicines in southwestern France.","finding":"","journal":"The Annals of pharmacotherapy","studyType":"Clinical Study"},{"pmid":"6121837","year":"1982","title":"Determination of the psychostimulants pemoline, fenozolone and thozalinone in human urine by gas chromatography/mass spectrometry and thin layer chromatography.","finding":"","journal":"Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie","studyType":"Clinical Study"}],"tags":[{"label":"fenozolone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N06BA08","category":"atc"},{"label":"Active","category":"status"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Sympathomimetics","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"phenozolone","offLabel":[],"synonyms":["LD 3394","LD-3394","fenozolone","phenozolone"],"timeline":[],"approvals":[],"brandName":"Phenozolone","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"fenozolone","explanation":"Imagine your body's cells are like locks, and the key to unlocking them is a specific target. Phenozolone is like a key that fits into this lock, but we don't know what the lock looks like or how it works yet. This means we can't be sure how it will affect the body or what side effects it might cause.","oneSentence":"Phenozolone works by interacting with a specific target in the body, but its exact mechanism is currently unknown.","technicalDetail":"Phenozolone's mechanism of action is currently unknown, and further research is needed to determine its pharmacological properties and potential therapeutic applications."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1157","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FENOZOLONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:25:50.805257","biosimilars":[],"competitors":[{"drugName":"amfetamine","drugSlug":"amfetamine","fdaApproval":"1955-09-09","relationship":"same-class"},{"drugName":"dexamfetamine","drugSlug":"dexamfetamine","fdaApproval":"1955-09-09","relationship":"same-class"},{"drugName":"methamphetamine","drugSlug":"methamphetamine","fdaApproval":"1943-12-31","genericCount":5,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"methylphenidate","drugSlug":"methylphenidate","fdaApproval":"1955-12-05","patentExpiry":"Jun 5, 2026","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"pemoline","drugSlug":"pemoline","fdaApproval":"1975-01-27","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"modafinil","drugSlug":"modafinil","fdaApproval":"1998-12-24","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"atomoxetine","drugSlug":"atomoxetine","fdaApproval":"2002-11-26","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"dexmethylphenidate","drugSlug":"dexmethylphenidate","fdaApproval":"2001-11-13","genericCount":19,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"lisdexamfetamine","drugSlug":"lisdexamfetamine","fdaApproval":"2007-02-23","patentExpiry":"Aug 30, 2040","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"armodafinil","drugSlug":"armodafinil","fdaApproval":"2007-06-05","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"solriamfetol","drugSlug":"solriamfetol","fdaApproval":"2019-03-20","patentExpiry":"Sep 5, 2037","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"serdexmethylphenidate","drugSlug":"serdexmethylphenidate","fdaApproval":"2021-03-02","relationship":"same-class"}],"genericName":"fenozolone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"amfetamine","brandName":"amfetamine","genericName":"amfetamine","approvalYear":"1955","relationship":"same-class"},{"drugId":"dexamfetamine","brandName":"dexamfetamine","genericName":"dexamfetamine","approvalYear":"1955","relationship":"same-class"},{"drugId":"methamphetamine","brandName":"methamphetamine","genericName":"methamphetamine","approvalYear":"1943","relationship":"same-class"},{"drugId":"methylphenidate","brandName":"methylphenidate","genericName":"methylphenidate","approvalYear":"1955","relationship":"same-class"},{"drugId":"pemoline","brandName":"pemoline","genericName":"pemoline","approvalYear":"1975","relationship":"same-class"},{"drugId":"modafinil","brandName":"modafinil","genericName":"modafinil","approvalYear":"1998","relationship":"same-class"},{"drugId":"atomoxetine","brandName":"atomoxetine","genericName":"atomoxetine","approvalYear":"2002","relationship":"same-class"},{"drugId":"dexmethylphenidate","brandName":"dexmethylphenidate","genericName":"dexmethylphenidate","approvalYear":"2001","relationship":"same-class"},{"drugId":"lisdexamfetamine","brandName":"lisdexamfetamine","genericName":"lisdexamfetamine","approvalYear":"2007","relationship":"same-class"},{"drugId":"armodafinil","brandName":"armodafinil","genericName":"armodafinil","approvalYear":"2007","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005419","UNII":"1NZI4LMU6G","CHEBI":"CHEBI:134865","INN_ID":"1694","RXNORM":"24860","UMLSCUI":"C0060187","ChEMBL_ID":"CHEMBL2104907","KEGG_DRUG":"D07344","DRUGBANK_ID":"DB13341","PUBCHEM_CID":"135436543","MESH_SUPPLEMENTAL_RECORD_UI":"C004996"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":8,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"N06BA08","allCodes":["N06BA08"]},"biosimilarFilings":[],"recentPublications":[{"date":"2005 Aug 15","pmid":"15950492","title":"Modulation of behavior and cortical motor activity in healthy subjects by a chronic administration of a serotonin enhancer.","journal":"NeuroImage"},{"date":"2002 Jan","pmid":"11771971","title":"A single dose of the serotonin neurotransmission agonist paroxetine enhances motor output: double-blind, placebo-controlled, fMRI study in healthy subjects.","journal":"NeuroImage"},{"date":"1999 Dec","pmid":"10598941","title":"Cerebral functional magnetic resonance imaging activation modulated by a single dose of the monoamine neurotransmission enhancers fluoxetine and fenozolone during hand sensorimotor tasks.","journal":"Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism"},{"date":"1997 Jul-Aug","pmid":"9220042","title":"Abuse of prescription medicines in southwestern France.","journal":"The Annals of pharmacotherapy"},{"date":"1982 Feb","pmid":"6121837","title":"Determination of the psychostimulants pemoline, fenozolone and thozalinone in human urine by gas chromatography/mass spectrometry and thin layer chromatography.","journal":"Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Phenozolone (FENOZOLONE) is a small molecule drug in the fenozolone class, but its target and mechanism of action are unknown. Its commercial status and approved indications are also unclear. As a result, key safety considerations and pharmacokinetic properties such as half-life and bioavailability are not well established. Further research is needed to fully understand this compound. Its ownership and patent status are also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}