{"id":"fenalcomine","rwe":[{"pmid":"7386277","year":"1980","title":"Fenalcomine hydrochloride inhibits the action of PG on the smooth muscle but stimulates that of TXA2.","finding":"","journal":"Advances in prostaglandin and thromboxane research","studyType":"Clinical Study"},{"pmid":"779586","year":"1976","title":"[Clinical study of fenalcomine chlorhydrate in 30 cases of angina pectoris].","finding":"","journal":"Annales de cardiologie et d'angeiologie","studyType":"Clinical Study"},{"pmid":"1096749","year":"1975","title":"[Study of the action of fenalcomine chlorhydrate using ergometric tests].","finding":"","journal":"Annales de cardiologie et d'angeiologie","studyType":"Clinical Study"},{"pmid":"1134178","year":"1975","title":"[Clinical study of a new anti-angina pectoris agent: Fenalcomine hydrochloride].","finding":"","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille","studyType":"Clinical Study"}],"tags":[{"label":"fenalcomine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"cordoxene","offLabel":[],"synonyms":["fenalcomine hydrochloride","cordoxene","fenalcomine"],"timeline":[],"approvals":[],"brandName":"Cordoxene","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"fenalcomine","explanation":"Imagine your body's cells have locks on them, and the key to unlocking the right response is a specific molecule. Fenalcomine is designed to fit into this lock, allowing the cell to respond in a way that treats a particular condition. This is a simplified explanation of how fenalcomine works at a molecular level.","oneSentence":"Fenalcomine is thought to work by interacting with a specific target in the body to produce a therapeutic effect.","technicalDetail":"Fenalcomine is a small molecule that binds to a specific receptor or enzyme, altering its activity and leading to a therapeutic effect. The exact mechanism of action is not well understood, but it is believed to involve modulation of a signaling pathway or neurotransmitter system."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1144","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FENALCOMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:14:23.461049","biosimilars":[],"competitors":[],"genericName":"fenalcomine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"1TBQ3A47P8","CHEBI":"CHEBI:135345","INN_ID":"3380","UMLSCUI":"C0060147","ChEMBL_ID":"CHEMBL2106300","PUBCHEM_CID":"71934","SECONDARY_CAS_RN":"34535-83-6","MESH_SUPPLEMENTAL_RECORD_UI":"C001424"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1980","pmid":"7386277","title":"Fenalcomine hydrochloride inhibits the action of PG on the smooth muscle but stimulates that of TXA2.","journal":"Advances in prostaglandin and thromboxane research"},{"date":"1976 May-Jun","pmid":"779586","title":"[Clinical study of fenalcomine chlorhydrate in 30 cases of angina pectoris].","journal":"Annales de cardiologie et d'angeiologie"},{"date":"1975 May-Jun","pmid":"1096749","title":"[Study of the action of fenalcomine chlorhydrate using ergometric tests].","journal":"Annales de cardiologie et d'angeiologie"},{"date":"1975 Jan","pmid":"1134178","title":"[Clinical study of a new anti-angina pectoris agent: Fenalcomine hydrochloride].","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cordoxene is a small molecule with the synonyms FENALCOMINA and FENALCOMINE. Its exact mechanism and indications are not specified in the provided information.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}