{"id":"fang-le-shu-follitrope","safety":{"commonSideEffects":[{"rate":null,"effect":"Ovarian hyperstimulation syndrome (OHSS)"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Abdominal pain/bloating"},{"rate":null,"effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Follitrope binds to FSH receptors on granulosa cells of ovarian follicles, promoting follicular development and estrogen production. This hormone replacement therapy is used in assisted reproductive technology to induce controlled ovarian hyperstimulation, enabling the retrieval of multiple mature oocytes for in vitro fertilization or other fertility procedures.","oneSentence":"Follitrope is a recombinant follicle-stimulating hormone (FSH) that stimulates the growth and maturation of ovarian follicles in women undergoing fertility treatment.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:46:15.746Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Infertility in women undergoing assisted reproductive technology (ART)"},{"name":"Anovulation and ovulatory dysfunction in women seeking fertility treatment"}]},"trialDetails":[{"nctId":"NCT06921395","phase":"PHASE4","title":"Phase IV Study to Evaluate the Efficacy and Safety of Fang Le Shu Compared to Guo Na Fen for Controlled Ovarian Stimulation in Infertile Women Undergoing in Vitro Fertilization-embryo Transfer (IVF-ET).","status":"RECRUITING","sponsor":"LG Chem","startDate":"2025-02-15","conditions":"Female Infertility","enrollment":248}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Fang Le Shu (Follitrope)","genericName":"Fang Le Shu (Follitrope)","companyName":"LG Chem","companyId":"lg-chem","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Follitrope is a recombinant follicle-stimulating hormone (FSH) that stimulates the growth and maturation of ovarian follicles in women undergoing fertility treatment. Used for Infertility in women undergoing assisted reproductive technology (ART), Anovulation and ovulatory dysfunction in women seeking fertility treatment.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}