{"id":"eziclen-izinova","safety":{"commonSideEffects":[{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Abdominal pain or cramping"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Eziclen contains sodium picosulfate, magnesium oxide, and citric acid, which together create an osmotic effect that draws water into the intestinal lumen and stimulates bowel movements. This combination cleanses the colon by promoting rapid transit of stool and intestinal contents, enabling clear visualization during colonoscopy or other lower gastrointestinal procedures.","oneSentence":"Eziclen is a bowel cleansing agent that works as an osmotic laxative to prepare the colon for endoscopic procedures.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:12:09.410Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bowel cleansing prior to colonoscopy or other lower gastrointestinal endoscopic procedures"}]},"trialDetails":[{"nctId":"NCT03008460","phase":"PHASE3","title":"Efficacy, Safety and Tolerability of Eziclen®/Izinova® Versus Klean-prep® on Bowel Cleansing in Adolescents Undergoing Colonoscopy","status":"COMPLETED","sponsor":"Ipsen","startDate":"2017-10-15","conditions":"Digestive System Disease","enrollment":250},{"nctId":"NCT02630680","phase":"","title":"Eziclen Drug Utilisation in Real Life Setting","status":"COMPLETED","sponsor":"Ipsen","startDate":"2015-10","conditions":"Bowel Cleansing","enrollment":1286}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Suprep®"],"phase":"phase_3","status":"active","brandName":"Eziclen®/Izinova®","genericName":"Eziclen®/Izinova®","companyName":"Ipsen","companyId":"ipsen","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Eziclen is a bowel cleansing agent that works as an osmotic laxative to prepare the colon for endoscopic procedures. Used for Bowel cleansing prior to colonoscopy or other lower gastrointestinal endoscopic procedures.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}