{"id":"eye-injection-mydrane","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient corneal edema"},{"rate":null,"effect":"Increased intraocular pressure"},{"rate":null,"effect":"Conjunctival injection"},{"rate":null,"effect":"Mydriasis-related visual disturbance"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Mydrane contains tropicamide (anticholinergic mydriatic), phenylephrine (alpha-1 adrenergic agonist), and lidocaine (local anesthetic). The combination produces rapid pupil dilation and corneal anesthesia without requiring separate injections, improving surgical efficiency and patient comfort during cataract procedures.","oneSentence":"Mydrane is a combination ophthalmic injection that dilates the pupil and provides anesthesia for cataract surgery by combining mydriatic and anesthetic agents.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:30:03.643Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Mydriasis and anesthesia during cataract surgery"}]},"trialDetails":[{"nctId":"NCT05925894","phase":"NA","title":"Efficacy Mydrane ® for Cataract Surgery in Patients With Concomitant Primary Open Angle Glaucoma.","status":"COMPLETED","sponsor":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","startDate":"2021-03-18","conditions":"Cataract Surgery","enrollment":60},{"nctId":"NCT04880928","phase":"PHASE4","title":"Comparison Mydriasis by Mydrane With Topical Drop Application","status":"COMPLETED","sponsor":"Medical University of Graz","startDate":"2020-08-12","conditions":"Cataract","enrollment":42},{"nctId":"NCT04396301","phase":"PHASE3","title":"Effect of Intracameral Injection of Mydriatic Plus Anaesthetic Combination on Corneal Endothelial Count in Phaco","status":"COMPLETED","sponsor":"Cairo University","startDate":"2019-02-01","conditions":"Corneal Endothelial Cell Loss, Mydriasis, Cataract","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":14,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Mydrane"],"phase":"marketed","status":"active","brandName":"Eye injection (Mydrane)","genericName":"Eye injection (Mydrane)","companyName":"Medical University of Graz","companyId":"medical-university-of-graz","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Mydrane is a combination ophthalmic injection that dilates the pupil and provides anesthesia for cataract surgery by combining mydriatic and anesthetic agents. Used for Mydriasis and anesthesia during cataract surgery.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}