{"id":"extract-psidii-guava","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Mild headache"},{"rate":null,"effect":"Allergic reaction (rare)"}]},"_chembl":{"chemblId":"CHEMBL2108766","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Guava leaf extract contains quercetin, kaempferol, and other flavonoids that act as free radical scavengers and inhibit pro-inflammatory cytokine production. These compounds may also modulate glucose metabolism and lipid profiles through multiple cellular signaling pathways. The extract's mechanism is primarily attributed to its antioxidant and anti-inflammatory properties rather than a single discrete molecular target.","oneSentence":"Psidium guava extract exerts therapeutic effects through its polyphenolic and antioxidant constituents, which reduce oxidative stress and modulate inflammatory pathways.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:46:34.360Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 2 diabetes mellitus"},{"name":"Dyslipidemia / Hyperlipidemia"}]},"trialDetails":[{"nctId":"NCT04810728","phase":"PHASE3","title":"Efficacy of Psidii Guava's Extract For COVID-19","status":"COMPLETED","sponsor":"Faculty of Medicine Baiturrahmah University","startDate":"2020-06-20","conditions":"Covid19","enrollment":90}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Psidii"],"phase":"phase_3","status":"active","brandName":"Extract Psidii guava","genericName":"Extract Psidii guava","companyName":"Faculty of Medicine Baiturrahmah University","companyId":"faculty-of-medicine-baiturrahmah-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Psidium guava extract exerts therapeutic effects through its polyphenolic and antioxidant constituents, which reduce oxidative stress and modulate inflammatory pathways. Used for Type 2 diabetes mellitus, Dyslipidemia / Hyperlipidemia.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}