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The 4% formulation is typically used for intravenous administration in acute acidosis management.","oneSentence":"Sodium bicarbonate neutralizes gastric acid and raises blood pH to treat acidosis and acid-related conditions.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:46:07.729Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Metabolic acidosis"},{"name":"Gastric acid neutralization"},{"name":"Urine alkalinization"}]},"trialDetails":[{"nctId":"NCT07318311","phase":"NA","title":"Comparative Evaluation of the Effect of pH Adjustment of the Solution of Articaine With Epinephrine on the Efficacy of Jet Anesthesia","status":"COMPLETED","sponsor":"Aristotle University Of Thessaloniki","startDate":"2022-08-01","conditions":"Comparative Evaluation of the Effect of pH Adjustment of the Solution of Articaine With Epinephrine on the Efficacy of Jet Anesthesia","enrollment":45},{"nctId":"NCT06525402","phase":"NA","title":"Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemotherapy","status":"RECRUITING","sponsor":"Burdur Mehmet Akif Ersoy University","startDate":"2025-01-30","conditions":"Oral Mucositis, Chemotherapy Effect","enrollment":54},{"nctId":"NCT04078022","phase":"PHASE2","title":"Shigella CVD 30000: Study of Responses to Vaccination With Shigella Vaccine","status":"COMPLETED","sponsor":"University of Maryland, Baltimore","startDate":"2020-03-02","conditions":"Shigella","enrollment":58},{"nctId":"NCT03570983","phase":"PHASE2","title":"A Trial Comparing Single Agent Melphalan to Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion","status":"UNKNOWN","sponsor":"Swedish Medical Center","startDate":"2018-09-05","conditions":"Multiple Myeloma","enrollment":100},{"nctId":"NCT03836144","phase":"","title":"Effect of Urine Alkalinazation on Urinary Inflammatory Markers in Patients With Cystinuria","status":"COMPLETED","sponsor":"European Georges Pompidou Hospital","startDate":"2015-04-02","conditions":"Cystinuria, Renal Lithiasis, Glomerulonephritis","enrollment":63},{"nctId":"NCT02082717","phase":"PHASE4","title":"The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis","status":"TERMINATED","sponsor":"Baptist Health South Florida","startDate":"2014-02-25","conditions":"Hypokalemia","enrollment":17},{"nctId":"NCT04800549","phase":"NA","title":"Effect of Black Mulberry Lollipop on Prevention of Oral Mucositis in Children","status":"COMPLETED","sponsor":"Sapanca Ilce Devlet Hastanesi","startDate":"2016-02","conditions":"Oral Mucositis","enrollment":69},{"nctId":"NCT02816346","phase":"PHASE1","title":"Dose-Finding Study of Lyophilized Shigella Sonnei 53G Challenge Strain","status":"COMPLETED","sponsor":"PATH","startDate":"2016-09-12","conditions":"Healthy","enrollment":56},{"nctId":"NCT02297399","phase":"PHASE3","title":"Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients","status":"COMPLETED","sponsor":"Parc de Salut Mar","startDate":"2014-12-02","conditions":"Diabetes Mellitus, Colonic Diseases","enrollment":158},{"nctId":"NCT01440478","phase":"PHASE1","title":"The Effects of Urinary pH Changes on an Investigational Compound in Healthy Subjects","status":"COMPLETED","sponsor":"Eli Lilly and Company","startDate":"2011-09","conditions":"Healthy Subjects","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":223,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Experimental - 4% Sodium Bicarbonate","genericName":"Experimental - 4% Sodium Bicarbonate","companyName":"Baptist Health South Florida","companyId":"baptist-health-south-florida","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Sodium bicarbonate neutralizes gastric acid and raises blood pH to treat acidosis and acid-related conditions. Used for Metabolic acidosis, Gastric acid neutralization, Urine alkalinization.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}