{"id":"evo100","safety":{"commonSideEffects":[{"rate":null,"effect":"Vaginal irritation"},{"rate":null,"effect":"Genital discomfort"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"EVO100 is a water-soluble vaginal film containing a spermicide that dissolves in vaginal fluid to create a contraceptive barrier. The film is designed to be inserted vaginally before intercourse and works by immobilizing and inactivating sperm, preventing fertilization. It offers a hormone-free contraceptive option for women seeking non-systemic birth control.","oneSentence":"EVO100 is a vaginal contraceptive film that provides non-hormonal contraception through a spermicidal mechanism.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:11:56.129Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Contraception in women of reproductive age"}]},"trialDetails":[{"nctId":"NCT04553068","phase":"PHASE3","title":"Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection","status":"COMPLETED","sponsor":"Evofem Inc.","startDate":"2020-10-15","conditions":"Sexually Transmitted Diseases, Gonorrhea, Chlamydia","enrollment":1892},{"nctId":"NCT03107377","phase":"PHASE2, PHASE3","title":"Phase 2B/3 Double-blinded Placebo-controlled","status":"COMPLETED","sponsor":"Evofem Inc.","startDate":"2017-11-03","conditions":"Chlamydia Trachomatis Infection","enrollment":860}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"EVO100","genericName":"EVO100","companyName":"Evofem Inc.","companyId":"evofem-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"EVO100 is a vaginal contraceptive film that provides non-hormonal contraception through a spermicidal mechanism. Used for Contraception in women of reproductive age.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":2},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}