{"id":"ev71vac","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain, erythema, or swelling"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Myalgia or fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains inactivated EV71 virus particles that trigger both humoral (antibody-mediated) and cell-mediated immune responses. This allows the vaccinated individual to recognize and neutralize EV71 upon natural exposure, preventing infection or reducing disease severity. The vaccine is designed to protect against hand, foot, and mouth disease (HFMD) and other serious EV71-associated complications, particularly in pediatric populations.","oneSentence":"EV71vac is an inactivated vaccine that stimulates the immune system to produce antibodies and cellular immunity against Enterovirus 71 (EV71).","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:11:48.742Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of Enterovirus 71 (EV71) infection and hand, foot, and mouth disease (HFMD) in pediatric populations"}]},"trialDetails":[{"nctId":"NCT03865238","phase":"PHASE3","title":"A Study to Evaluate the Efficacy, Safety, and Immunogenicity of an EV71 Vaccine","status":"COMPLETED","sponsor":"Medigen Vaccine Biologics Corp.","startDate":"2019-04-23","conditions":"Enterovirus 71 Infection","enrollment":3061}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"EV71vac","genericName":"EV71vac","companyName":"Medigen Vaccine Biologics Corp.","companyId":"medigen-vaccine-biologics-corp","modality":"Biologic","firstApprovalDate":"","aiSummary":"EV71vac is an inactivated vaccine that stimulates the immune system to produce antibodies and cellular immunity against Enterovirus 71 (EV71). Used for Prevention of Enterovirus 71 (EV71) infection and hand, foot, and mouth disease (HFMD) in pediatric populations.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}