{"id":"eucalyptus-oil","_fda":{"id":"401d7f62-3537-e928-e063-6294a90a178e","set_id":"00f2fd0e-2608-6c06-e063-6294a90a066a","openfda":{"upc":["0323900039216"],"unii":["5TJD82A1ET","2R04ONI662","L7T10EIP3A"],"route":["TOPICAL"],"rxcui":["727137"],"spl_id":["401d7f62-3537-e928-e063-6294a90a178e"],"brand_name":["Vicks childrens VapoRub"],"spl_set_id":["00f2fd0e-2608-6c06-e063-6294a90a066a"],"package_ndc":["58933-595-50"],"product_ndc":["58933-595"],"generic_name":["CAMPHOR (SYNTHETIC), EUCALYPTUS OIL, MENTHOL"],"product_type":["HUMAN OTC DRUG"],"substance_name":["CAMPHOR (SYNTHETIC)","EUCALYPTUS OIL","MENTHOL"],"manufacturer_name":["Procter & Gamble Manufactura S de RL de CV"],"application_number":["M012"],"is_original_packager":[true]},"purpose":["Purpose Cough suppressant & topical analgesic Cough suppressant Cough suppressant & topical analgesic"],"version":"6","stop_use":["Stop use and ask a doctor if muscle aches and pains worsen or persist for more than 7 days or clear up and occur again within a few days. cough persists for more than 1 week, tends to recur, or is accompanied by fever, rash, or persistent headache. A persistent cough may be a sign of a serious condition."],"warnings":["Warnings For external use only; avoid contact with eyes."],"questions":["Questions? 1-800-873-8276"],"ask_doctor":["Ask a doctor before use if you have cough that occurs with too much phlegm (mucus) persistent or chronic cough such as occurs with smoking, asthma or emphysema"],"do_not_use":["Do not use by mouth in nostrils on wounds or damaged skin with tight bandages"],"overdosage":["If swallowed, get medical help or contact a Poison Control Center right away."],"when_using":["When using this product, do not heat microwave add to hot water or any container where heating water. May cause splattering and result in burns."],"effective_time":"20251001","active_ingredient":["Camphor (synthetic) 4.8% Eucalyptus oil 1.2% Menthol 2.6% Purpose Cough suppressant & topical analgesic Cough suppressant Cough suppressant & topical analgesic"],"inactive_ingredient":["Inactive ingredients cedarleaf oil, nutmeg oil, petrolatum, thymol, turpentine oil"],"storage_and_handling":["Other information store at room temperature"],"indications_and_usage":["Uses when applied to chest and throat, temporarily relieves cough due to minor throat and bronchial irritation associated with the common cold when applied to muscles and joints, temporarily relieves minor aches and pains of muscles and joints"],"spl_unclassified_section":["Drug Facts","Keep carton for future reference. TAMPER EVIDENT: Carton sealed for your protection.","MADE IN MEXICO DIST. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"],"dosage_and_administration":["Directions see important warnings under \"When using this product\" adults and children 2 years and over: for cough suppression rub a thick layer on throat & chest cover with a warm, dry cloth if desired keep clothing loose about throat and chest to help vapors reach the nose and mouth use up to three times daily or as directed by doctor for muscle / joint minor aches and pains apply to affected area not more than 3 to 4 times daily children under 2 years: do not use"],"spl_product_data_elements":["Vicks childrens VapoRub Camphor (synthetic), Eucalyptus oil, Menthol PETROLATUM CEDAR LEAF OIL NUTMEG OIL THYMOL TURPENTINE OIL CAMPHOR (SYNTHETIC) CAMPHOR (SYNTHETIC) EUCALYPTUS OIL EUCALYPTUS OIL MENTHOL MENTHOL"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"keep_out_of_reach_of_children":["Keep out of reach of children."],"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 50 g Jar Carton VICKS ® children's VapoRub™ COUGH SUPPRESSANT TOPICAL ANALGESIC Ointment 2+ years NET WT 1.76 OZ (50 g) 595"]},"safety":{"boxedWarnings":[]},"_chembl":{"chemblId":"CHEMBL2108406","moleculeType":"Unknown"},"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=EUCALYPTUS OIL","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T04:50:31.120566+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-20T04:50:53.194342+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T04:50:37.167545+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=EUCALYPTUS OIL","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T04:50:37.619954+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T04:50:29.930638+00:00"},"indications.approved":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-20T04:50:48.679327+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T04:50:29.930668+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL2108406/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T04:50:38.391277+00:00"},"regulatory.fda_application":{"url":"","method":"deterministic","source":"FDA Label","rawText":"M012","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T04:50:29.930671+00:00"}},"_dailymed":{"setId":"2d56ddcd-3cc8-51eb-e063-6394a90ae745","title":"WALGREENS CHEST RUB (CAMPHOR, EUCALYPTUS OIL, MENTHOL) OINTMENT [WALGREEN COMPANY]"},"aiSummary":"EUCALYPTUS OIL is a marketed product primarily indicated for cough relief due to the common cold. The key composition patent is set to expire in 2028, providing a clear timeline for potential generic competition. The primary risk is the lack of significant revenue data and key trial results, which may limit its market competitiveness.","_scrapedAt":"2026-03-28T03:06:40.285Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":2,"lastValidatedAt":"2026-04-20T04:50:53.194478+00:00","fieldsConflicting":0,"overallConfidence":0.95},"indications":{"approved":[{"id":"eucalyptus-oil-cough-relief-due-to-common-col","name":"Cough relief due to common cold","dosing":null,"approvals":[],"diseaseId":"","eligibility":"Individuals with minor throat and bronchial irritation due to the common cold","pivotalTrial":null,"restrictions":[],"patientPopulation":"Individuals with minor throat and bronchial irritation due to the common cold","diagnosticRequired":null,"brandNameForIndication":""},{"id":"eucalyptus-oil-muscle-and-joint-pain-relief","name":"Muscle and joint pain relief","dosing":null,"approvals":[],"diseaseId":"","eligibility":"Individuals with minor aches and pains of muscles and joints","pivotalTrial":null,"restrictions":[],"patientPopulation":"Individuals with minor aches and pains of muscles and joints","diagnosticRequired":null,"brandNameForIndication":""}]},"trialDetails":[{"nctId":"NCT07221123","phase":"EARLY_PHASE1","title":"Boosting Olfactory and Sensory Training Study (BOOST)","status":"NOT_YET_RECRUITING","sponsor":"University of Alabama at Birmingham","startDate":"2026-05-01","conditions":"HIV (Human Immunodeficiency Virus)","enrollment":80},{"nctId":"NCT05912881","phase":"NA","title":"Chemosensory Dysfunction and Recovery in Endoscopic Endonasal Skull Base Surgery","status":"COMPLETED","sponsor":"Johns Hopkins University","startDate":"2023-02-01","conditions":"Anosmia, Skull Base Neoplasms","enrollment":41},{"nctId":"NCT05175521","phase":"NA","title":"Inhaled IAV vs Inhaled Eucalyptus for the Treatment of Nausea With Acute Migraine","status":"ACTIVE_NOT_RECRUITING","sponsor":"HonorHealth Research Institute","startDate":"2021-11-11","conditions":"Migraine","enrollment":50},{"nctId":"NCT07103460","phase":"NA","title":"Essential Oil-Assisted Respiratory Training in Type 2 Diabetic Patients With Lung Infections","status":"NOT_YET_RECRUITING","sponsor":"National Taipei University of Nursing and Health Sciences","startDate":"2025-07-25","conditions":"Type 2 Diabetes Mellitus (T2DM), Pulmonary Infections, Pneumonia","enrollment":100},{"nctId":"NCT04374474","phase":"PHASE4","title":"Anosmia Rehabilitation in Patients Post Coronavirus Disease (COVID 19)","status":"WITHDRAWN","sponsor":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","startDate":"2021-01-10","conditions":"Olfactory Disorder","enrollment":""},{"nctId":"NCT03441074","phase":"NA","title":"Olfactory Function and Delayed Neurocognitive Recovery","status":"COMPLETED","sponsor":"Shanghai 10th People's Hospital","startDate":"2018-01-01","conditions":"Delayed Neurocognitive Recovery","enrollment":131},{"nctId":"NCT07093138","phase":"PHASE4","title":"Evaluation of Efficacy and Safety of Topical Cannabidiol (Canvert-M Produced by Alasht Pharmed co. 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