{"id":"ethylhydrocupreine","rwe":[{"pmid":"29445727","year":"2018","title":"Molecular Features Underlying Selectivity in Chicken Bitter Taste Receptors.","finding":"","journal":"Frontiers in molecular biosciences","studyType":"Clinical Study"},{"pmid":"28811548","year":"2017","title":"Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case.","finding":"","journal":"Scientific reports","studyType":"Clinical Study"},{"pmid":"16415127","year":"2006","title":"Identification of new antimalarial drugs by linear discriminant analysis and topological virtual screening.","finding":"","journal":"The Journal of antimicrobial chemotherapy","studyType":"Clinical Study"},{"pmid":"15386953","year":"2004","title":"Changing interest among physicians toward pneumococcal vaccination throughout the twentieth century.","finding":"","journal":"Journal of the history of medicine and allied sciences","studyType":"Clinical Study"},{"pmid":"15313529","year":"2004","title":"Comparison of four polymerase chain reaction assays for specificity in the identification of Streptococcus pneumoniae.","finding":"","journal":"Diagnostic microbiology and infectious disease","studyType":"Clinical Study"}],"tags":[{"label":"ethylhydrocupreine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"numoquin","offLabel":[],"synonyms":["ethylhydrocupreine","numoquin","optichin","ethylhydrocupreine hydrochloride","ethylhydrocupreine HCl"],"timeline":[],"approvals":[],"brandName":"Numoquin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"ethylhydrocupreine","explanation":"Think of Numoquin like a magnet that attracts and holds onto copper ions in the body. This can help reduce the amount of copper available to cause problems in cells. By chelating copper, Numoquin may help alleviate symptoms associated with copper overload or imbalance.","oneSentence":"Numoquin works by chelating copper ions, which are involved in various cellular processes.","technicalDetail":"As a chelating agent, ethylhydrocupreine binds to copper ions through its hydroxamic acid group, forming a stable complex that can be excreted from the body."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Optochin","title":"Optochin","extract":"Optochin is a derivative of quinine introduced in 1911 by Morgenroth and Levy with the intention to treat pneumococci infection. In very high dilutions, it inhibits the growth of representatives of all four groups of pneumococci in vitro. That is the main reason it is now used in bacteriology for the differentiation of Streptococcus pneumoniae, which is optochin-sensitive, from the other, resistant alpha-hemolytic streptococci, sometimes called the viridans streptococci because of the green colouration on blood agar around colonies."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3740","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ethylhydrocupreine","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Optochin","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T11:16:45.282942","biosimilars":[],"competitors":[],"genericName":"ethylhydrocupreine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"4W030VS2OG","CHEBI":"CHEBI:86455","UMLSCUI":"C0059828","ChEMBL_ID":"CHEMBL548228","PUBCHEM_CID":"87880","SECONDARY_CAS_RN":"3413-58-9","MESH_SUPPLEMENTAL_RECORD_UI":"C017303"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":8,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2018","pmid":"29445727","title":"Molecular Features Underlying Selectivity in Chicken Bitter Taste Receptors.","journal":"Frontiers in molecular biosciences"},{"date":"2017 Aug 15","pmid":"28811548","title":"Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case.","journal":"Scientific reports"},{"date":"2006 Mar","pmid":"16415127","title":"Identification of new antimalarial drugs by linear discriminant analysis and topological virtual screening.","journal":"The Journal of antimicrobial chemotherapy"},{"date":"2004 Oct","pmid":"15386953","title":"Changing interest among physicians toward pneumococcal vaccination throughout the twentieth century.","journal":"Journal of the history of medicine and allied sciences"},{"date":"2004 Aug","pmid":"15313529","title":"Comparison of four polymerase chain reaction assays for specificity in the identification of Streptococcus pneumoniae.","journal":"Diagnostic microbiology and infectious disease"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Optochin is a derivative of quinine introduced in 1911 by Morgenroth and Levy to treat pneumococci infection. It is used in bacteriology to differentiate Streptococcus pneumoniae, which is optochin-sensitive, from other pneumococci.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}