{"id":"ethylenediamine-dihydrochloride-allergen-patch","safety":{"commonSideEffects":[{"rate":null,"effect":"Localized skin irritation or allergic reaction at patch site"},{"rate":null,"effect":"Erythema and induration at test site"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This compound is applied to the skin via a patch test to provoke a localized allergic reaction in sensitized individuals, allowing clinicians to identify contact allergen sensitivities. The reaction occurs through T-cell mediated immune response (Type IV hypersensitivity) when the allergen contacts skin in previously sensitized patients. It is used diagnostically rather than therapeutically.","oneSentence":"Ethylenediamine dihydrochloride serves as a contact allergen in patch testing to diagnose delayed-type hypersensitivity reactions and allergic contact dermatitis.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:45:59.732Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Diagnostic patch testing for ethylenediamine contact allergy and delayed-type hypersensitivity reactions"}]},"trialDetails":[{"nctId":"NCT01798589","phase":"PHASE4","title":"Bioequivalence of Ethylenediamine Dihydrochloride Study","status":"COMPLETED","sponsor":"Allerderm","startDate":"2012-07","conditions":"Allergic Contact Dermatitis","enrollment":16}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["T.R.U.E. Test allergen ethylenediamine dihydrochloride"],"phase":"marketed","status":"active","brandName":"Ethylenediamine dihydrochloride allergen patch","genericName":"Ethylenediamine dihydrochloride allergen patch","companyName":"Allerderm","companyId":"allerderm","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ethylenediamine dihydrochloride serves as a contact allergen in patch testing to diagnose delayed-type hypersensitivity reactions and allergic contact dermatitis. Used for Diagnostic patch testing for ethylenediamine contact allergy and delayed-type hypersensitivity reactions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}