{"id":"ethoheptazine","rwe":[{"pmid":"2960369","year":"1987","title":"Mefenamic acid, chlormezanone-paracetamol, ethoheptazine-aspirin-meprobamate: a comparative study in acute low back pain.","finding":"","journal":"The British journal of clinical practice","studyType":"Clinical Study"},{"pmid":"6643621","year":"1983","title":"Determination of ethoheptazine in human post mortem material.","finding":"","journal":"Journal of chromatography","studyType":"Clinical Study"},{"pmid":"41087","year":"1979","title":"Investigation of narcotics and antitussives using drug discrimination techniques.","finding":"","journal":"The Journal of pharmacology and experimental therapeutics","studyType":"Clinical Study"},{"pmid":"44372","year":"1979","title":"Effects of propoxyphene, ethoheptazine, and azabicyclane on schedule-controlled responding: attenuation by pentobarbital but not naloxone.","finding":"","journal":"Psychopharmacology","studyType":"Clinical Study"},{"pmid":"4214668","year":"1974","title":"Treatment of musculoskeletal pain and associated anxiety with an ethoheptazine-aspirin-meprobamate combination (equagesic): a controlled study.","finding":"","journal":"Current therapeutic research, clinical and experimental","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"contraindications":["Acute abdominal pain","Alcohol intoxication","Alcohol withdrawal delirium","Asthenia","Benign intracranial hypertension","Benign prostatic hyperplasia","Bradycardia","Central nervous system depression","Coma","Conduction disorder of the heart","Constipation","Cor pulmonale","Decreased respiratory function","Dehydration","Dependent drug abuse","Disease of liver","Disorder of gallbladder","Drug-induced psychosis","Dysfunction of sphincter of Oddi","Exacerbation of asthma","Hypercapnia","Hypothyroidism","Hypoxia","Inflammatory bowel disease","Injury of head","Kidney disease","Lesion of brain","Low blood pressure","Mood swings","Morbid obesity","Neoplasm of brain","Operation on gastrointestinal tract","Primary adrenocortical insufficiency","Pulmonary emphysema","Retention of urine","Seizure disorder","Shock","Substance abuse","Suicidal thoughts","Ulcerative colitis","Urethral stricture"]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"aethoheptazin","offLabel":[],"synonyms":["ethoheptazine citrate","ethoheptazine","aethoheptazin","ethyl heptazine"],"timeline":[],"aiSummary":"Aethoheptazine, also known as ETHOHEPTAZINE, is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it is not known whether it is FDA approved or off-patent. The approved indications for Aethoheptazine are also unknown. As a small molecule, it is likely to work by interacting with specific biological molecules to produce a therapeutic effect. Further research is needed to fully understand its mechanism of action and safety profile.","approvals":[],"brandName":"Aethoheptazin","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your brain is like a computer, and Aethoheptazine is like a software update that helps fix problems with how your brain is working. It does this by interacting with tiny molecules called receptors in the brain, which helps to regulate how your brain processes information and responds to stimuli.","oneSentence":"Aethoheptazine is thought to work by interacting with the central nervous system to produce a therapeutic effect.","technicalDetail":"Aethoheptazine is a small molecule that likely acts as a receptor agonist or antagonist, modulating the activity of specific neurotransmitter systems in the central nervous system."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1085","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ETHOHEPTAZINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:07:57.175542","biosimilars":[],"competitors":[],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"ethoheptazine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"NUI":"N0000147357","NDDF":"001577","UNII":"3A4G3A848U","VUID":"4019099","CHEBI":"CHEBI:31567","VANDF":"4019099","INN_ID":"573","RXNORM":"235416","UMLSCUI":"C0059725","ChEMBL_ID":"CHEMBL170797","KEGG_DRUG":"D01435","DRUGBANK_ID":"DB08988","PUBCHEM_CID":"6469","SNOMEDCT_US":"64940005","SECONDARY_CAS_RN":"6700-56-7","MESH_SUPPLEMENTAL_RECORD_UI":"C100067"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":19,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1987 Feb","pmid":"2960369","title":"Mefenamic acid, chlormezanone-paracetamol, ethoheptazine-aspirin-meprobamate: a comparative study in acute low back pain.","journal":"The British journal of clinical practice"},{"date":"1983 Oct 14","pmid":"6643621","title":"Determination of ethoheptazine in human post mortem material.","journal":"Journal of chromatography"},{"date":"1979 Nov","pmid":"41087","title":"Investigation of narcotics and antitussives using drug discrimination techniques.","journal":"The Journal of pharmacology and experimental therapeutics"},{"date":"1979","pmid":"44372","title":"Effects of propoxyphene, ethoheptazine, and azabicyclane on schedule-controlled responding: attenuation by pentobarbital but not naloxone.","journal":"Psychopharmacology"},{"date":"1974 Sep","pmid":"4214668","title":"Treatment of musculoskeletal pain and associated anxiety with an ethoheptazine-aspirin-meprobamate combination (equagesic): a controlled study.","journal":"Current therapeutic research, clinical and experimental"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}