{"id":"etaqualone","rwe":[{"pmid":"39508427","year":"2025","title":"From historical drugs to present perils: UHPLC-QqQ-MS/MS determination of methaqualone and its designer analogs (NPS) with comprehensive fragmentation pathways study (QTOF).","finding":"","journal":"Toxicology mechanisms and methods","studyType":"Clinical Study"},{"pmid":"36652055","year":"2023","title":"The next addiction-causing drug class 4-quinazolinone derivatives: analyses of methaqualone analogs including recently discovered 2-methoxyqualone by different modes of mass spectrometry.","finding":"","journal":"Forensic toxicology","studyType":"Clinical Study"},{"pmid":"35932525","year":"2022","title":"Analytical method for detection and quantification of new emerging drug etaqualone in human blood and urine by gas chromatography tandem mass spectrometry.","finding":"","journal":"Legal medicine (Tokyo, Japan)","studyType":"Clinical Study"},{"pmid":"34521032","year":"2021","title":"Detection and quantification of psychotropic drug etaqualone in human hair using GC-MS/MS.","finding":"","journal":"Legal medicine (Tokyo, Japan)","studyType":"Clinical Study"}],"tags":[{"label":"etaqualone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"athinazone","offLabel":[],"synonyms":["etaqualone","athinazone","ethinazone"],"timeline":[],"approvals":[],"brandName":"Athinazone","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"etaqualone","explanation":"Imagine your brain is a city with many different neighborhoods. Athinazone is like a special key that unlocks certain doors in the city, but we don't know which doors or how it affects the city's traffic. This means we don't know exactly how it helps or harms people who take it.","oneSentence":"Athinazone is thought to work by interacting with the central nervous system, but its exact mechanism of action is not well understood.","technicalDetail":"Athinazone is a small molecule that likely interacts with specific receptors or ion channels in the central nervous system, but the precise molecular mechanisms underlying its effects are unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3192","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ETAQUALONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:05:35.944252","biosimilars":[],"competitors":[],"genericName":"etaqualone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"HFS3HB32J7","CHEBI":"CHEBI:135090","INN_ID":"2256","UMLSCUI":"C1880564","ChEMBL_ID":"CHEMBL2104633","PUBCHEM_CID":"23914"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2025 Mar","pmid":"39508427","title":"From historical drugs to present perils: UHPLC-QqQ-MS/MS determination of methaqualone and its designer analogs (NPS) with comprehensive fragmentation pathways study (QTOF).","journal":"Toxicology mechanisms and methods"},{"date":"2023 Jan","pmid":"36652055","title":"The next addiction-causing drug class 4-quinazolinone derivatives: analyses of methaqualone analogs including recently discovered 2-methoxyqualone by different modes of mass spectrometry.","journal":"Forensic toxicology"},{"date":"2022 Nov","pmid":"35932525","title":"Analytical method for detection and quantification of new emerging drug etaqualone in human blood and urine by gas chromatography tandem mass spectrometry.","journal":"Legal medicine (Tokyo, Japan)"},{"date":"2021 Nov","pmid":"34521032","title":"Detection and quantification of psychotropic drug etaqualone in human hair using GC-MS/MS.","journal":"Legal medicine (Tokyo, Japan)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Athinazone (ETAQUALONE) is a small molecule drug of the etaqualone class, but its target and exact mechanism of action are unknown. It is not FDA-approved for any indications. The commercial status of Athinazone is unclear, and it may be patented or off-patent. Key safety considerations are not well-documented. Further research is needed to understand its pharmacological properties and potential therapeutic applications.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}