{"id":"estrogen-herbals-28","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Estrogen Herbals 28 is a botanical supplement containing multiple herbs traditionally used to support hormonal balance. The formulation likely contains plants with phytoestrogenic compounds that may bind to estrogen receptors or modulate estrogen metabolism, though the exact active constituents and their individual contributions are not well-characterized in standard pharmaceutical literature.","oneSentence":"This herbal formulation provides phytoestrogens and plant-derived compounds that mimic or support estrogen activity in the body.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:45:54.552Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Menopausal symptom support (presumed, based on product name)"}]},"trialDetails":[{"nctId":"NCT02618148","phase":"PHASE4","title":"Hormone Estradiol Replacement Therapy Additional Herbals","status":"COMPLETED","sponsor":"Trieu, Nguyen Thi, M.D.","startDate":"2009-01","conditions":"Menopause","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":71,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["EPGANA 28"],"phase":"marketed","status":"active","brandName":"ESTROGEN HERBALS 28","genericName":"ESTROGEN HERBALS 28","companyName":"Trieu, Nguyen Thi, M.D.","companyId":"trieu-nguyen-thi-m-d","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This herbal formulation provides phytoestrogens and plant-derived compounds that mimic or support estrogen activity in the body. Used for Menopausal symptom support (presumed, based on product name).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}