{"id":"estradiol-undecylate","rwe":[],"tags":[{"label":"Estrogen","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Estrogens","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"oestradiol undecylate","offLabel":[],"synonyms":["estradiol undecylate","oestradiol undecylate"],"timeline":[],"approvals":[],"brandName":"Oestradiol Undecylate","ecosystem":[],"mechanism":{"moaClass":"Estrogen Receptor Agonists","modality":"Small Molecule","drugClass":"Estrogen","explanation":"Imagine your body has locks on cells that only estrogen can open. Oestradiol Undecylate is a key that fits into these locks, allowing estrogen to do its job and influencing things like bone health, skin health, and the menstrual cycle.","oneSentence":"Oestradiol Undecylate works by binding to estrogen receptors in the body, influencing various physiological processes.","technicalDetail":"Oestradiol Undecylate is a prodrug of estradiol, which binds to estrogen receptors (ERα and ERβ) in a tissue-specific manner, activating downstream signaling pathways that regulate gene expression and cellular function."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1063","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ESTRADIOL UNDECYLATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:13:22.795289","biosimilars":[],"competitors":[],"genericName":"estradiol undecylate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"4684","NDDF":"001265","UNII":"H3N3A8MFJC","CHEBI":"CHEBI:135719","VANDF":"4017609","INN_ID":"2014","RXNORM":"4083","UMLSCUI":"C0771510","ChEMBL_ID":"CHEMBL1697794","KEGG_DRUG":"D04065","DRUGBANK_ID":"DB00783","PDB_CHEM_ID":" EST","PUBCHEM_CID":"19135","SNOMEDCT_US":"126172005","MESH_DESCRIPTOR_UI":"D004958"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Bone"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Oestradiol Undecylate is a small molecule estrogen medication with an unknown target. Its exact mechanism of action is not well-documented, but it is believed to work by binding to estrogen receptors in the body, influencing various physiological processes. The medication's commercial status and approved indications are unknown. As an estrogen medication, it may be used to treat conditions related to estrogen deficiency or imbalance. However, due to the lack of information, its safety profile and potential side effects cannot be fully assessed.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}