{"id":"eschscholzia-tablets","safety":{"commonSideEffects":[{"rate":null,"effect":"Drowsiness"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Gastrointestinal upset"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The plant contains alkaloids such as californine and other compounds that may enhance GABAergic neurotransmission and promote relaxation. These constituents are believed to reduce nervous tension and support natural sleep patterns without the potency of synthetic sedatives. The exact molecular mechanisms remain incompletely characterized but are consistent with traditional herbal use for anxiety and sleep support.","oneSentence":"Eschscholzia californica (California poppy) extract acts as a mild sedative and anxiolytic agent, likely through modulation of GABAergic and other neurotransmitter systems.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:11:34.723Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anxiety and nervous tension"},{"name":"Sleep disturbances and insomnia support"}]},"trialDetails":[{"nctId":"NCT06795776","phase":"PHASE3","title":"Eschscholzia Study","status":"COMPLETED","sponsor":"A. Vogel AG","startDate":"2025-04-07","conditions":"Sleep","enrollment":104},{"nctId":"NCT05300594","phase":"NA","title":"Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus.","status":"COMPLETED","sponsor":"CEN Biotech","startDate":"2022-03-01","conditions":"Tinnitus","enrollment":110}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Eschscholzia tablets","genericName":"Eschscholzia tablets","companyName":"A. Vogel AG","companyId":"a-vogel-ag","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Eschscholzia californica (California poppy) extract acts as a mild sedative and anxiolytic agent, likely through modulation of GABAergic and other neurotransmitter systems. Used for Anxiety and nervous tension, Sleep disturbances and insomnia support.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}