{"id":"erdosteine","rwe":[{"pmid":"41688985","year":"2026","title":"Efficacy and safety of mucolytic agents in patients with chronic obstructive pulmonary disease: a systematic review and network meta-analysis.","finding":"","journal":"BMC pulmonary medicine","studyType":"Clinical Study"},{"pmid":"41351371","year":"2025","title":"Glycation-mediated binding defect in human serum albumin transport of erdosteine: implications in diabetes.","finding":"","journal":"Cellular and molecular biology (Noisy-le-Grand, France)","studyType":"Clinical Study"},{"pmid":"40859807","year":"2025","title":"Efficacy and safety of HL-301 compared with erdosteine in acute bronchitis: a randomized, double-blind, non-inferiority trial.","finding":"","journal":"The Korean journal of internal medicine","studyType":"Clinical Study"},{"pmid":"40761281","year":"2025","title":"Exploring the effects of resveratrol and β-hydroxy-β-methylbutyric acid under different protein levels on the ileal health of tibetan sheep.","finding":"","journal":"Frontiers in microbiology","studyType":"Clinical Study"},{"pmid":"40362318","year":"2025","title":"Interaction of Erdosteine with TrkA Signaling Pathways: Implications for Analgesia.","finding":"","journal":"International journal of molecular sciences","studyType":"Clinical Study"}],"tags":[{"label":"erdosteine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"R05CB15","category":"atc"},{"label":"Active","category":"status"},{"label":"Accidental poisoning by lead and its compounds and fumes","category":"indication"},{"label":"Mercury Toxicity","category":"indication"},{"label":"Expectorants","category":"pharmacology"},{"label":"Respiratory System Agents","category":"pharmacology"}],"phase":"phase_3","safety":{"safetySignals":[{"llr":39.461,"date":"","count":37,"signal":"Pneumonia","source":"DrugCentral FAERS","actionTaken":"Reported 37 times (LLR=39)"}],"commonSideEffects":[{"effect":"Pneumonia","drugRate":"LLR 39","severity":"common"}]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"dithiosteine","offLabel":[],"synonyms":["erdosteine","dithiosteine"],"timeline":[],"approvals":[],"brandName":"Dithiosteine","ecosystem":[{"indication":"Accidental poisoning by lead and its compounds and fumes","otherDrugs":[{"name":"dimercaprol","slug":"dimercaprol","company":"Akorn"},{"name":"edetic acid","slug":"edetic-acid","company":"Medicis"},{"name":"succimer","slug":"succimer","company":"Recordati Rare"}],"globalPrevalence":null},{"indication":"Mercury Toxicity","otherDrugs":[{"name":"dimercaprol","slug":"dimercaprol","company":"Akorn"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"erdosteine","explanation":"Imagine Erdosteine as a special kind of 'mop' that helps clean up heavy metals like lead and mercury from your body. 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