{"id":"eprotirome-and-ezetimibe","safety":{"commonSideEffects":[{"rate":"null","effect":"Musculoskeletal pain"},{"rate":"null","effect":"Liver enzyme elevations"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Eprotirome works by blocking thyroid hormone receptors, which can help reduce thyroid hormone levels in the body. Ezetimibe, on the other hand, inhibits the absorption of cholesterol in the small intestine, leading to decreased cholesterol levels in the blood.","oneSentence":"Eprotirome is a thyroid hormone receptor antagonist, and ezetimibe is a cholesterol absorption inhibitor.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:51:36.253Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypercholesterolemia"}]},"trialDetails":[{"nctId":"NCT00677248","phase":"PHASE2","title":"LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe","status":"COMPLETED","sponsor":"Karo Bio AB","startDate":"2008-04","conditions":"Hypercholesterolemia","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Eprotirome and ezetimibe","genericName":"Eprotirome and ezetimibe","companyName":"Karo Bio AB","companyId":"karo-bio-ab","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Eprotirome is a thyroid hormone receptor antagonist, and ezetimibe is a cholesterol absorption inhibitor. Used for Hypercholesterolemia.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}