{"id":"epomediol","rwe":[],"tags":[{"label":"epomediol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A05BA05","category":"atc"},{"label":"Active","category":"status"},{"label":"Cholagogues and Choleretics","category":"pharmacology"},{"label":"Gastrointestinal Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"clesidren","offLabel":[],"synonyms":["epomediol","2,6-Dihydroxycineol","clesidren"],"timeline":[],"approvals":[],"brandName":"Clesidren","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"epomediol","explanation":"Imagine your body's cells have locks on them, and the key to opening those locks is a specific shape. Clesidren is like a key that fits into those locks, changing how the cells work. This can help to treat certain conditions, but more research is needed to understand exactly how it works.","oneSentence":"Clesidren works by binding to a specific target and altering its activity.","technicalDetail":"Clesidren's mechanism of action is not well-documented, but it is believed to involve binding to a specific protein or receptor, leading to changes in cellular activity. Further research is needed to fully understand its pharmacology and potential therapeutic applications."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Epomediol","title":"Epomediol","extract":"Epomediol is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1033","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=epomediol","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Epomediol","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T11:03:59.952660","biosimilars":[],"competitors":[{"drugName":"glycyrrhizic acid","drugSlug":"glycyrrhizic-acid","fdaApproval":"","relationship":"same-class"}],"genericName":"epomediol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"glycyrrhizic-acid","brandName":"glycyrrhizic acid","genericName":"glycyrrhizic acid","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"007163","UNII":"KFU4XSK3BK","CHEBI":"CHEBI:81225","RXNORM":"24263","UMLSCUI":"C0059459","ChEMBL_ID":"CHEMBL3707255","DRUGBANK_ID":"DB13802","PUBCHEM_CID":"115056","SECONDARY_CAS_RN":"1310101-21-3","MESH_SUPPLEMENTAL_RECORD_UI":"C031365"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":31,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"A05BA05","allCodes":["A05BA05"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Clesidren, also known as Epomediol, is a synthetic terpenoid with choleretic effects. It is used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}