{"id":"enocitabine","rwe":[{"pmid":"29973453","year":"2018","title":"[Acute myeloid leukemia of the elderly: recent progresses in therapy].","finding":"","journal":"[Rinsho ketsueki] The Japanese journal of clinical hematology","studyType":"Clinical Study"},{"pmid":"22956429","year":"2012","title":"Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study.","finding":"","journal":"International journal of hematology","studyType":"Clinical Study"},{"pmid":"20052341","year":"2010","title":"Idarubicin plus behenoyl cytarabine and 6-thioguanine compares favorably with idarubicin plus cytarabine-based regimen for children with previously untreated acute myeloid leukemia: 10-year retrospective, multicenter study in Korea.","finding":"","journal":"Journal of Korean medical science","studyType":"Clinical Study"},{"pmid":"18030012","year":"2007","title":"[A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute].","finding":"","journal":"Gan to kagaku ryoho. 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By doing so, it prevents the virus from making copies of itself, which can help slow down the progression of the infection. This mechanism is specific to viral replication and is distinct from how our own cells replicate DNA.","oneSentence":"Sunrabin works by incorporating itself into viral DNA, thereby disrupting its replication and transcription.","technicalDetail":"Sunrabin acts as a nucleoside analog, incorporating itself into the viral DNA strand through the action of viral reverse transcriptase. Once incorporated, Sunrabin's presence triggers the activation of viral DNA polymerase, leading to the formation of a stable but non-functional DNA strand that cannot be replicated or transcribed."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1012","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ENOCITABINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:00:24.650916","biosimilars":[],"competitors":[],"genericName":"enocitabine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"372","NDDF":"002649","UNII":"9YVR68W306","CHEBI":"CHEBI:31537","VANDF":"4018080","INN_ID":"5121","RXNORM":"3041","UMLSCUI":"C0059364","ChEMBL_ID":"CHEMBL2106589","KEGG_DRUG":"D01633","DRUGBANK_ID":"DB00987","PDB_CHEM_ID":" AR3","PUBCHEM_CID":"71734","SNOMEDCT_US":"387511003","MESH_DESCRIPTOR_UI":"D003561","MESH_SUPPLEMENTAL_RECORD_UI":"C015019"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":34,"therapeuticAreas":["Metabolic"],"biosimilarFilings":[],"recentPublications":[{"date":"2018","pmid":"29973453","title":"[Acute myeloid leukemia of the elderly: recent progresses in therapy].","journal":"[Rinsho ketsueki] The Japanese journal of clinical hematology"},{"date":"2012 Oct","pmid":"22956429","title":"Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study.","journal":"International journal of hematology"},{"date":"2010 Jan","pmid":"20052341","title":"Idarubicin plus behenoyl cytarabine and 6-thioguanine compares favorably with idarubicin plus cytarabine-based regimen for children with previously untreated acute myeloid leukemia: 10-year retrospective, multicenter study in Korea.","journal":"Journal of Korean medical science"},{"date":"2007 Nov","pmid":"18030012","title":"[A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute].","journal":"Gan to kagaku ryoho. 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