{"id":"enfenamic-acid","rwe":[{"pmid":"2633972","year":"1989","title":"Lysosomal membrane stabilization by antiinflammatory drugs.","finding":"","journal":"Indian journal of experimental biology","studyType":"Clinical Study"},{"pmid":"2757224","year":"1989","title":"Extractive spectrophotometric determination of some anti-inflammatory agents with methylene violet.","finding":"","journal":"The Analyst","studyType":"Clinical Study"},{"pmid":"3229792","year":"1988","title":"Wound healing profile of copper salts of enfenamic acid & ibuprofen.","finding":"","journal":"The Indian journal of medical research","studyType":"Clinical Study"},{"pmid":"3169962","year":"1988","title":"Effects of enfenamic acid and its zinc salt on wound-healing.","finding":"","journal":"Indian journal of physiology and pharmacology","studyType":"Clinical Study"},{"pmid":"3436650","year":"1987","title":"Erythrocyte membrane stabilization by enfenamic acid.","finding":"","journal":"Indian journal of experimental biology","studyType":"Clinical Study"}],"tags":[{"label":"enfenamic acid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Analgesics","category":"pharmacology"},{"label":"Analgesics, Non-Narcotic","category":"pharmacology"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Anti-Inflammatory Agents, Non-Steroidal","category":"pharmacology"},{"label":"Antirheumatic Agents","category":"pharmacology"},{"label":"Hematologic Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Platelet Aggregation Inhibitors","category":"pharmacology"},{"label":"Sensory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tromaril","offLabel":[],"synonyms":["enfenamic acid","tromaril"],"timeline":[],"approvals":[],"brandName":"Tromaril","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"enfenamic acid","explanation":"Think of prostaglandins like messengers that tell your body to feel pain and become inflamed. Tromaril blocks these messengers, which can help reduce pain and swelling. This can be especially helpful for people with conditions like arthritis or menstrual cramps.","oneSentence":"Tromaril works by inhibiting the production of prostaglandins, which are hormone-like substances that cause pain and inflammation.","technicalDetail":"Enfenamic acid, the active ingredient in Tromaril, is a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, thereby reducing the production of prostaglandins and thromboxanes."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3176","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ENFENAMIC ACID","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:56:06.754953","biosimilars":[],"competitors":[],"genericName":"enfenamic acid","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"05KO5G76R2","CHEBI":"CHEBI:134983","INN_ID":"4973","UMLSCUI":"C0116077","ChEMBL_ID":"CHEMBL2106178","PUBCHEM_CID":"31635","MESH_SUPPLEMENTAL_RECORD_UI":"C019126"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":14,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"recentPublications":[{"date":"1989 Dec","pmid":"2633972","title":"Lysosomal membrane stabilization by antiinflammatory drugs.","journal":"Indian journal of experimental biology"},{"date":"1989 Apr","pmid":"2757224","title":"Extractive spectrophotometric determination of some anti-inflammatory agents with methylene violet.","journal":"The Analyst"},{"date":"1988 Sep","pmid":"3229792","title":"Wound healing profile of copper salts of enfenamic acid & ibuprofen.","journal":"The Indian journal of medical research"},{"date":"1988 Jan-Mar","pmid":"3169962","title":"Effects of enfenamic acid and its zinc salt on wound-healing.","journal":"Indian journal of physiology and pharmacology"},{"date":"1987 Jul","pmid":"3436650","title":"Erythrocyte membrane stabilization by enfenamic acid.","journal":"Indian journal of experimental biology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tromaril is a small molecule. It is also known by the synonyms ACIDE ENFENAMIQUE, ACIDO ENFENAMICO, and ENFENAMIC ACID.","enrichmentLevel":3,"visitCount":2,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}