{"id":"ems-acarbose","safety":{"commonSideEffects":[{"rate":"20-30","effect":"Gastrointestinal disturbances (flatulence, diarrhea, abdominal discomfort)"},{"rate":"10-20","effect":"Abdominal pain"},{"rate":"15-25","effect":"Diarrhea"}]},"_chembl":{"chemblId":"CHEMBL4299399","moleculeType":"Small molecule","molecularWeight":"645.61"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Acarbose is an alpha-glucosidase inhibitor that delays the breakdown and absorption of disaccharides and polysaccharides in the small intestine. By slowing glucose absorption, it reduces postprandial blood glucose peaks in patients with type 2 diabetes. This mechanism helps improve glycemic control without stimulating insulin secretion.","oneSentence":"Acarbose inhibits intestinal alpha-glucosidase enzymes to slow carbohydrate digestion and reduce postprandial glucose spikes.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:46:12.259Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 2 diabetes mellitus"}]},"trialDetails":[{"nctId":"NCT01316861","phase":"PHASE3","title":"Efficacy and Safety of Oral Acarbose Treatment in Patients With Type 2 Diabetes Mellitus","status":"COMPLETED","sponsor":"EMS","startDate":"2012-09","conditions":"Type 2 Diabetes Mellitus","enrollment":79}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"EMS Acarbose","genericName":"EMS Acarbose","companyName":"EMS","companyId":"ems","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Acarbose inhibits intestinal alpha-glucosidase enzymes to slow carbohydrate digestion and reduce postprandial glucose spikes. Used for Type 2 diabetes mellitus.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}