{"id":"embramine","rwe":[{"pmid":"28145326","year":"1987","title":"Relative Efficacy of Seven Common H1 Receptor Antagonist Antihistamines in Chronic Idiopathic Urticaria.","finding":"","journal":"Indian journal of dermatology, venereology and leprology","studyType":"Clinical Study"},{"pmid":"3602052","year":"1987","title":"Content uniformity test of tablets by nonaqueous titration method.","finding":"","journal":"Die Pharmazie","studyType":"Clinical Study"}],"tags":[{"label":"embramine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Histamine Agents","category":"pharmacology"},{"label":"Histamine Antagonists","category":"pharmacology"},{"label":"Histamine H1 Antagonists","category":"pharmacology"},{"label":"Neurotransmitter Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bromadryl","offLabel":[],"synonyms":["embramine hydrochloride","embramine HCl","mebrophenhydramine","bromadryl","embramine"],"timeline":[],"approvals":[],"brandName":"Bromadryl","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"embramine","explanation":"Imagine your brain is a complex computer with many different chemical signals. Bromadryl helps regulate these signals, which can help treat conditions where the signals are out of balance. This can lead to feelings of calmness and reduced anxiety.","oneSentence":"Bromadryl works by affecting the levels of certain chemicals in the brain.","technicalDetail":"Bromadryl is a serotonin-norepinephrine reuptake inhibitor (SNRI), which means it increases the levels of serotonin and norepinephrine in the brain by blocking their reabsorption into neurons."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/998","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=EMBRAMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:54:49.018287","biosimilars":[],"competitors":[],"genericName":"embramine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"HH0KD7Z416","CHEBI":"CHEBI:135472","INN_ID":"1784","UMLSCUI":"C0059053","ChEMBL_ID":"CHEMBL2110819","KEGG_DRUG":"D07889","PUBCHEM_CID":"19105","SECONDARY_CAS_RN":"13977-28-1","MESH_SUPPLEMENTAL_RECORD_UI":"C005715"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1987 May-Jun","pmid":"28145326","title":"Relative Efficacy of Seven Common H1 Receptor Antagonist Antihistamines in Chronic Idiopathic Urticaria.","journal":"Indian journal of dermatology, venereology and leprology"},{"date":"1987 Feb","pmid":"3602052","title":"Content uniformity test of tablets by nonaqueous titration method.","journal":"Die Pharmazie"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bromadryl, also known as EMBRAMINE, is a small molecule drug in the embramine class. Its exact target is unknown, but it is used to treat certain conditions. The commercial status of Bromadryl is unclear, and it may be patented or have generic manufacturers. Key safety considerations are not well-documented. Further research is needed to fully understand this medication.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}