{"id":"eg-007","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Hypokalemia"},{"rate":"5-10%","effect":"Fatigue"},{"rate":"5-10%","effect":"Dizziness"}]},"_chembl":{"chemblId":"CHEMBL3702600","moleculeType":"Small molecule","molecularWeight":"308.39"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting the sodium-potassium pump, EG-007 aims to reduce the workload on the heart, thereby alleviating symptoms of heart failure. This is achieved by reducing the heart's energy expenditure and improving its pumping efficiency.","oneSentence":"EG-007 is a selective inhibitor of the sodium- potassium pump.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:46:09.785Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Symptomatic heart failure"},{"name":"Reducing the risk of cardiovascular death and hospitalization in heart failure"}]},"trialDetails":[{"nctId":"NCT05106127","phase":"PHASE2","title":"Safety Lead-In Study of a Repurposed Drug Added to the Combination of Len Plus Pem","status":"NOT_YET_RECRUITING","sponsor":"Evergreen Therapeutics, Inc.","startDate":"2026-08","conditions":"Advanced Endometrial Cancer","enrollment":28},{"nctId":"NCT05077215","phase":"PHASE3","title":"Efficacy and Safety of a Repurposed Drug Added to the Combination of Len Plus Pem in Advanced Endometrial Cancer","status":"NOT_YET_RECRUITING","sponsor":"Evergreen Therapeutics, Inc.","startDate":"2026-12","conditions":"Advanced Endometrial Cancer","enrollment":450}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"EG-007","genericName":"EG-007","companyName":"Evergreen Therapeutics, Inc.","companyId":"evergreen-therapeutics-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"EG-007 is a selective inhibitor of the sodium- potassium pump. Used for Symptomatic heart failure, Reducing the risk of cardiovascular death and hospitalization in heart failure.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}