{"id":"dpt-ipv-hib-low-combined-vaccine","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain, redness, or swelling"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Irritability or fussiness"},{"rate":null,"effect":"Drowsiness"}]},"_chembl":{"chemblId":"CHEMBL2108573","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"DPT-IPV-Hib is a pentavalent inactivated vaccine that contains antigens from five pathogens. It works by presenting these antigens to the immune system, triggering both humoral (antibody-mediated) and cell-mediated immune responses. This primes the immune system to recognize and neutralize these pathogens upon future exposure, providing protection against these five infectious diseases.","oneSentence":"This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b pathogens.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:45:57.262Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b infection in infants and children"}]},"trialDetails":[{"nctId":"NCT02992925","phase":"PHASE3","title":"Phase 3 Study of BK1310 in Healthy Infants","status":"COMPLETED","sponsor":"Tanabe Pharma Corporation","startDate":"2016-11","conditions":"Immunization; Infection","enrollment":370}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":730,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["BK1310-Low"],"phase":"phase_3","status":"active","brandName":"DPT-IPV-Hib-Low（Combined Vaccine）","genericName":"DPT-IPV-Hib-Low（Combined Vaccine）","companyName":"Tanabe Pharma Corporation","companyId":"tanabe-pharma-corporation","modality":"Biologic","firstApprovalDate":"","aiSummary":"This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b pathogens. Used for Prevention of diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b infection in infants and children.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}