{"id":"dpt-ipv-hib-high-combined-vaccine","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain, redness, or swelling"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Irritability or fussiness"},{"rate":null,"effect":"Drowsiness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"DPT-IPV-Hib is a pentavalent inactivated vaccine that contains antigens from five pathogens. Upon administration, it triggers both humoral (antibody-mediated) and cell-mediated immune responses, leading to the production of protective antibodies against toxins and surface antigens of these bacteria and viruses. This provides immunological memory for long-term protection against these infectious diseases.","oneSentence":"This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:10:00.159Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b infection in infants and children"}]},"trialDetails":[{"nctId":"NCT02992925","phase":"PHASE3","title":"Phase 3 Study of BK1310 in Healthy Infants","status":"COMPLETED","sponsor":"Tanabe Pharma Corporation","startDate":"2016-11","conditions":"Immunization; Infection","enrollment":370}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":730,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["BK1310-High"],"phase":"phase_3","status":"active","brandName":"DPT-IPV-Hib-High（Combined Vaccine）","genericName":"DPT-IPV-Hib-High（Combined Vaccine）","companyName":"Tanabe Pharma Corporation","companyId":"tanabe-pharma-corporation","modality":"Biologic","firstApprovalDate":"","aiSummary":"This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b. Used for Prevention of diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b infection in infants and children.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}