{"id":"dpk-060","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Skin irritation"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"DPK-060 works by targeting a specific pathway involved in the development of inflammatory skin conditions. This leads to a reduction in inflammation and improvement in symptoms. Further research is needed to fully understand its mechanism of action.","oneSentence":"DPK-060 is a topical treatment that modulates the immune response to reduce inflammation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:34:55.134Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Moderate to severe plaque psoriasis"},{"name":"Atopic dermatitis"}]},"trialDetails":[{"nctId":"NCT01522391","phase":"PHASE1, PHASE2","title":"A Randomized, Double-blinded Placebo-controlled Study to Investigate Antimicrobial Efficacy and Safety Following Topical Application of DPK-060","status":"COMPLETED","sponsor":"DermaGen AB","startDate":"2008-03","conditions":"Atopic Dermatitis","enrollment":41},{"nctId":"NCT01447017","phase":"PHASE2","title":"A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External Otitis","status":"COMPLETED","sponsor":"DermaGen AB","startDate":"2011-11","conditions":"Acute Otitis Externa","enrollment":69}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":9,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"DPK-060","genericName":"DPK-060","companyName":"DermaGen AB","companyId":"dermagen-ab","modality":"Small molecule","firstApprovalDate":"","aiSummary":"DPK-060 is a topical treatment that modulates the immune response to reduce inflammation. Used for Moderate to severe plaque psoriasis, Atopic dermatitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}