{"id":"dlx105-hydrogel","safety":{"commonSideEffects":[{"rate":"null","effect":"Numbness"},{"rate":"null","effect":"Tingling"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"DLX105 Hydrogel works by releasing a local anesthetic to provide pain relief. The exact mechanism of action is not well understood, but it is thought to involve the inhibition of sodium channels in nerve cells, preventing the transmission of pain signals.","oneSentence":"DLX105 Hydrogel is a hydrogel formulation of a local anesthetic.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T02:33:35.163Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Postoperative pain management"}]},"trialDetails":[{"nctId":"NCT01936337","phase":"PHASE2","title":"Topical Double-blind, Randomized, Placebo-controlled Study in Psoriasis Patients","status":"COMPLETED","sponsor":"Delenex Therapeutics AG","startDate":"2013-08","conditions":"Psoriasis Vulgaris","enrollment":59}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"DLX105 Hydrogel","genericName":"DLX105 Hydrogel","companyName":"Delenex Therapeutics AG","companyId":"delenex-therapeutics-ag","modality":"Small molecule","firstApprovalDate":"","aiSummary":"DLX105 Hydrogel is a small molecule intervention being studied for the treatment of Psoriasis Vulgaris in a Phase II clinical trial. It is a topical hydrogel formulation, likely containing hypochlorous acid, which is being compared to a placebo in a double-blind, randomized study.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}