{"id":"dixanthogen","rwe":[{"pmid":"35796995","year":"2022","title":"The effect of experimental conditions on the formation of dixanthogen by triiodide oxidation in the determination of ethyl xanthate by HPLC-ICP-MS/MS.","finding":"","journal":"Analytical sciences : the international journal of the Japan Society for Analytical Chemistry","studyType":"Clinical Study"},{"pmid":"15780312","year":"2005","title":"Molecular modeling study on the relative stabilities of the flotation products for arsenic-containing minerals: dixanthogens and arsenic(III) xanthates.","finding":"","journal":"Journal of colloid and interface science","studyType":"Clinical Study"},{"pmid":"1699338","year":"1990","title":"[Treatment of scabies now as the dixanthogen ointment 5 and 10 per cent is no longer available].","finding":"","journal":"Ugeskrift for laeger","studyType":"Clinical Study"},{"pmid":"18964204","year":"1986","title":"Determination of trace amounts of the flotation collectors ethyl xanthate and diethyl dithiophosphate in aqueous solutions by cathodic stripping voltammetry.","finding":"","journal":"Talanta","studyType":"Clinical Study"},{"pmid":"93335","year":"1979","title":"[Treatment of scabies with hexicide and dixanthogen].","finding":"","journal":"Ugeskrift for laeger","studyType":"Clinical Study"}],"tags":[{"label":"dixanthogen","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P03AA01","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bexide","offLabel":[],"synonyms":["dixanthogen","auligen","aulinogen","bexide","bisethylxanthogen","bisethylxanthogen disulfide","diethyl dixanthogen","diethylxanthogen disulfide","scabicidol","sulfasan","thioperoxydicarbonic acid diethyl ester"],"timeline":[],"approvals":[],"brandName":"Bexide","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"dixanthogen","explanation":"Imagine your body's cells have locks on them, and Bexide is a key that fits into one of those locks. When it binds to the lock, it triggers a series of events that ultimately lead to a therapeutic effect. However, the exact lock that Bexide binds to and the events that follow are not yet fully understood.","oneSentence":"Bexide works by interacting with a specific molecular target to produce a therapeutic effect.","technicalDetail":"Bexide is a small molecule dixanthogen that modulates the activity of a specific protein or receptor, leading to a downstream effect on cellular function."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3163","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=DIXANTHOGEN","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIXANTHOGEN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:43:49.772001","biosimilars":[],"competitors":[{"drugName":"disulfiram","drugSlug":"disulfiram","fdaApproval":"1951-08-28","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"dixanthogen","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"disulfiram","brandName":"disulfiram","genericName":"disulfiram","approvalYear":"1951","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT00799734","phase":"NA","title":"Chinese Medicine Therapy on Menopausal Symptoms","status":"COMPLETED","sponsor":"The University of Hong Kong","startDate":"2009-04","conditions":["Menopause"],"enrollment":108,"completionDate":"2011-06"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"RN4CQ46FDM","CHEBI":"CHEBI:82241","INN_ID":"84","UMLSCUI":"C0058517","ChEMBL_ID":"CHEMBL331743","KEGG_DRUG":"D07366","DRUGBANK_ID":"DB13712","PUBCHEM_CID":"10404","MESH_SUPPLEMENTAL_RECORD_UI":"C000171"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":12,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"P03AA01","allCodes":["P03AA01"]},"biosimilarFilings":[],"recentPublications":[{"date":"2022 Sep","pmid":"35796995","title":"The effect of experimental conditions on the formation of dixanthogen by triiodide oxidation in the determination of ethyl xanthate by HPLC-ICP-MS/MS.","journal":"Analytical sciences : the international journal of the Japan Society for Analytical Chemistry"},{"date":"2005 Apr 15","pmid":"15780312","title":"Molecular modeling study on the relative stabilities of the flotation products for arsenic-containing minerals: dixanthogens and arsenic(III) xanthates.","journal":"Journal of colloid and interface science"},{"date":"1990 Sep 17","pmid":"1699338","title":"[Treatment of scabies now as the dixanthogen ointment 5 and 10 per cent is no longer available].","journal":"Ugeskrift for laeger"},{"date":"1986 Oct","pmid":"18964204","title":"Determination of trace amounts of the flotation collectors ethyl xanthate and diethyl dithiophosphate in aqueous solutions by cathodic stripping voltammetry.","journal":"Talanta"},{"date":"1979 Oct 22","pmid":"93335","title":"[Treatment of scabies with hexicide and dixanthogen].","journal":"Ugeskrift for laeger"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bexide, also known as a dixanthogen, is a small molecule drug with an unknown target. Its exact mechanism of action and approved indications are not publicly available. The commercial status of Bexide is also unclear, with no information on patent status or generic manufacturers. Further research is needed to understand the pharmacological properties and safety considerations of this compound. As a result, Bexide is not a well-characterized drug.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}