{"id":"ditazole","rwe":[{"pmid":"8559495","year":"1995","title":"Haemodynamic changes induced by the correction of anaemia by erythropoietin: role of antiplatelet therapy.","finding":"","journal":"Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association","studyType":"Clinical Study"},{"pmid":"2907728","year":"1988","title":"On the metabolism of ditazole in man.","finding":"","journal":"Arzneimittel-Forschung","studyType":"Clinical Study"},{"pmid":"6151552","year":"1984","title":"In vitro investigation on the antiaggregating activity of ditazole.","finding":"","journal":"International journal of clinical pharmacology research","studyType":"Clinical Study"},{"pmid":"6147319","year":"1984","title":"Effect of a single Ditazole dose on platelet aggregation and prostaglandin formation.","finding":"","journal":"International journal of clinical pharmacology research","studyType":"Clinical Study"},{"pmid":"6140774","year":"1983","title":"The vascular protection of ditazole and its effect on arachidonic acid metabolism.","finding":"","journal":"Thrombosis research","studyType":"Clinical Study"}],"tags":[{"label":"ditazole","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"B01AC01","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"ditazol","offLabel":[],"synonyms":["ditazole","ageroplas","diethylphenazol","ditazol"],"timeline":[],"approvals":[],"brandName":"Ditazol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"ditazole","explanation":"Imagine your body's cells have a factory inside them that produces energy. Ditazol is like a key that tries to fit into a lock to stop the factory from working too fast. However, since the exact mechanism is unknown, it's hard to say exactly how it affects the body's energy production.","oneSentence":"Ditazol is thought to work by inhibiting a specific enzyme or protein, although the exact mechanism is unknown.","technicalDetail":"Ditazol is a ditazole class compound, but its precise mechanism of action and target are currently unknown, making it difficult to provide detailed technical information."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/929","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DITAZOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:43:38.678566","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:07:44.376862+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[{"drugName":"clopidogrel","drugSlug":"clopidogrel","fdaApproval":"1997-11-17","genericCount":23,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ticlopidine","drugSlug":"ticlopidine","fdaApproval":"1991-10-31","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"acetylsalicylic acid","drugSlug":"acetylsalicylic-acid","fdaApproval":"1950-04-12","relationship":"same-class"},{"drugName":"dipyridamole","drugSlug":"dipyridamole","fdaApproval":"1961-12-06","genericCount":17,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"epoprostenol","drugSlug":"epoprostenol","fdaApproval":"1995-09-20","patentExpiry":"Mar 15, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"iloprost","drugSlug":"iloprost","fdaApproval":"2004-12-29","patentExpiry":"Jul 18, 2044","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"abciximab","drugSlug":"abciximab","fdaApproval":"1993-12-16","relationship":"same-class"},{"drugName":"eptifibatide","drugSlug":"eptifibatide","fdaApproval":"1998-05-18","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"tirofiban","drugSlug":"tirofiban","fdaApproval":"1998-05-14","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"treprostinil","drugSlug":"treprostinil","fdaApproval":"2002-05-21","patentExpiry":"Sep 5, 2028","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"prasugrel","drugSlug":"prasugrel","fdaApproval":"2009-07-10","genericCount":10,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"cilostazol","drugSlug":"cilostazol","fdaApproval":"1999-01-15","genericCount":12,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ticagrelor","drugSlug":"ticagrelor","fdaApproval":"2011-07-20","patentExpiry":"Oct 17, 2030","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"cangrelor","drugSlug":"cangrelor","fdaApproval":"2015-06-22","patentExpiry":"Nov 10, 2030","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"vorapaxar","drugSlug":"vorapaxar","fdaApproval":"2014-05-08","patentExpiry":"Dec 23, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"selexipag","drugSlug":"selexipag","fdaApproval":"2015-12-21","patentExpiry":"Oct 31, 2026","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"ditazole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"clopidogrel","brandName":"clopidogrel","genericName":"clopidogrel","approvalYear":"1997","relationship":"same-class"},{"drugId":"ticlopidine","brandName":"ticlopidine","genericName":"ticlopidine","approvalYear":"1991","relationship":"same-class"},{"drugId":"acetylsalicylic-acid","brandName":"acetylsalicylic acid","genericName":"acetylsalicylic acid","approvalYear":"1950","relationship":"same-class"},{"drugId":"dipyridamole","brandName":"dipyridamole","genericName":"dipyridamole","approvalYear":"1961","relationship":"same-class"},{"drugId":"epoprostenol","brandName":"epoprostenol","genericName":"epoprostenol","approvalYear":"1995","relationship":"same-class"},{"drugId":"iloprost","brandName":"iloprost","genericName":"iloprost","approvalYear":"2004","relationship":"same-class"},{"drugId":"abciximab","brandName":"abciximab","genericName":"abciximab","approvalYear":"1993","relationship":"same-class"},{"drugId":"eptifibatide","brandName":"eptifibatide","genericName":"eptifibatide","approvalYear":"1998","relationship":"same-class"},{"drugId":"tirofiban","brandName":"tirofiban","genericName":"tirofiban","approvalYear":"1998","relationship":"same-class"},{"drugId":"treprostinil","brandName":"treprostinil","genericName":"treprostinil","approvalYear":"2002","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"H2BQI5Z8FT","CHEBI":"CHEBI:135383","INN_ID":"2603","UMLSCUI":"C0012777","ChEMBL_ID":"CHEMBL2104306","KEGG_DRUG":"D07138","DRUGBANK_ID":"DB08994","PUBCHEM_CID":"29088","MESH_SUPPLEMENTAL_RECORD_UI":"C084774"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":17,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"B01AC01","allCodes":["B01AC01"]},"biosimilarFilings":[],"recentPublications":[{"date":"1995","pmid":"8559495","title":"Haemodynamic changes induced by the correction of anaemia by erythropoietin: role of antiplatelet therapy.","journal":"Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association"},{"date":"1988 Dec","pmid":"2907728","title":"On the metabolism of ditazole in man.","journal":"Arzneimittel-Forschung"},{"date":"1984","pmid":"6151552","title":"In vitro investigation on the antiaggregating activity of ditazole.","journal":"International journal of clinical pharmacology research"},{"date":"1984","pmid":"6147319","title":"Effect of a single Ditazole dose on platelet aggregation and prostaglandin formation.","journal":"International journal of clinical pharmacology research"},{"date":"1983 Dec 1","pmid":"6140774","title":"The vascular protection of ditazole and its effect on arachidonic acid metabolism.","journal":"Thrombosis research"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ditazol, also known as DITAZOLE, is a small molecule drug in the ditazole class. Its original development is attributed to an unknown entity, and its current ownership is also unclear. The exact target of Ditazol is unknown, and it has not been approved by the FDA for any indications. As a result, there is limited information available on its commercial status, pharmacokinetics, or safety profile. Further research is needed to fully understand Ditazol's properties and potential applications.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:07:44.376862+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}