{"id":"disofenin","rwe":[{"pmid":"30000627","year":"2006","title":"Technetium Tc 99m Disofenin.","finding":"","journal":"","studyType":"Clinical Study"},{"pmid":"25097073","year":"2014","title":"Beyond current guidelines: reduction in minimum administered radiopharmaceutical activity with preserved diagnostic image quality in pediatric hepatobiliary scintigraphy.","finding":"","journal":"European journal of nuclear medicine and molecular imaging","studyType":"Clinical Study"},{"pmid":"19249514","year":"2009","title":"Nuclear imaging of the liver: is there a diagnostic role of HIDA in posttransplantation?","finding":"","journal":"Transplantation proceedings","studyType":"Clinical Study"},{"pmid":"16960695","year":"2007","title":"Usefulness of magnetic resonance cholangiopancreatography in biliary structures in infants: a four-case report.","finding":"","journal":"European journal of pediatrics","studyType":"Clinical Study"},{"pmid":"16896007","year":"2006","title":"Relationship of hepatic functional imaging to irinotecan pharmacokinetics and genetic parameters of drug elimination.","finding":"","journal":"Journal of clinical oncology : official journal of the American Society of Clinical Oncology","studyType":"Clinical Study"}],"tags":[{"label":"disofenin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"disida","offLabel":[],"synonyms":["disofenin","DISIDA"],"timeline":[],"approvals":[],"brandName":"Disida","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"disofenin","explanation":"Imagine your body's cells have locks on them, and Disida has a key that fits into one of these locks. When Disida binds to its target, it can either block or enhance the activity of the cell, depending on the specific mechanism of action. However, without knowing the identity of the target, it's difficult to understand exactly how Disida works.","oneSentence":"Disida works by binding to a specific target, but the identity of this target is unknown.","technicalDetail":"As a disofenin, Disida likely acts as a competitive inhibitor or agonist at its target receptor, but the precise molecular details of its interaction are not available."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3161","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DISOFENIN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:43:18.431056","biosimilars":[],"competitors":[],"genericName":"disofenin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000147403","MMSL":"28973","NDDF":"009837","UNII":"4V891LH5NB","VUID":"4019158","CHEBI":"CHEBI:135480","VANDF":"4019158","INN_ID":"4786","RXNORM":"314599","UMLSCUI":"C0982128","ChEMBL_ID":"CHEMBL1615780","KEGG_DRUG":"D03873","DRUGBANK_ID":"DB09164","PUBCHEM_CID":"171682"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":84,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2006","pmid":"30000627","title":"Technetium Tc 99m Disofenin.","journal":""},{"date":"2014 Dec","pmid":"25097073","title":"Beyond current guidelines: reduction in minimum administered radiopharmaceutical activity with preserved diagnostic image quality in pediatric hepatobiliary scintigraphy.","journal":"European journal of nuclear medicine and molecular imaging"},{"date":"2009 Jan-Feb","pmid":"19249514","title":"Nuclear imaging of the liver: is there a diagnostic role of HIDA in posttransplantation?","journal":"Transplantation proceedings"},{"date":"2007 Mar","pmid":"16960695","title":"Usefulness of magnetic resonance cholangiopancreatography in biliary structures in infants: a four-case report.","journal":"European journal of pediatrics"},{"date":"2006 Sep 10","pmid":"16896007","title":"Relationship of hepatic functional imaging to irinotecan pharmacokinetics and genetic parameters of drug elimination.","journal":"Journal of clinical oncology : official journal of the American Society of Clinical Oncology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Disida (DISOFENIN) is a small molecule drug of the disofenin class, but specific details about its target, pharmacokinetics, and commercial status are not available. It is unclear whether Disida has been approved by the FDA or is available as a generic medication. The exact indications for Disida are also unknown. Further research is needed to determine the safety and efficacy of Disida. As a result, it is not possible to provide a comprehensive summary of Disida's commercial status or key safety considerations.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}