{"id":"disci-rhus-toxicodendron-comp","safety":{"commonSideEffects":[{"rate":null,"effect":"Homeopathic aggravation (temporary symptom exacerbation)"},{"rate":null,"effect":"Allergic reaction to Rhus toxicodendron component"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Disci/Rhus toxicodendron comp. is a classical homeopathic preparation that combines Rhus toxicodendron with other ingredients. In homeopathic theory, it is intended to work through immune tolerance mechanisms, potentially desensitizing the immune system to allergens or inflammatory triggers. The mechanism is based on homeopathic principles rather than conventional pharmacology.","oneSentence":"A homeopathic combination remedy containing Rhus toxicodendron (poison ivy) and other botanical components designed to modulate immune tolerance and reduce inflammatory responses.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:09:38.124Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Contact dermatitis and allergic skin reactions"},{"name":"Rheumatoid arthritis and joint inflammation"}]},"trialDetails":[{"nctId":"NCT00567736","phase":"PHASE3","title":"Efficacy of Disci/Rhus Toxicodendron Comp.®, in Patients With Chronic Low Back Pain","status":"COMPLETED","sponsor":"Charite University, Berlin, Germany","startDate":"2007-08","conditions":"Chronic Low Back Pain","enrollment":150}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Disci/Rhus toxicodendron comp.®","genericName":"Disci/Rhus toxicodendron comp.®","companyName":"Charite University, Berlin, Germany","companyId":"charite-university-berlin-germany","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A homeopathic combination remedy containing Rhus toxicodendron (poison ivy) and other botanical components designed to modulate immune tolerance and reduce inflammatory responses. Used for Contact dermatitis and allergic skin reactions, Rheumatoid arthritis and joint inflammation.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}