{"id":"dipiproverine","rwe":[{"pmid":"14205397","year":"1964","title":"[THE USE OF DIPIPROVERINE DURING THE VICHY THERMAL CURE IN THE TREATMENT OF BILIARY DYSKINESIA AND SPASMODIC COLOPATHIES. (DOCUMENTARY AND STATISTICAL STUDY APROPOS OF 98 CASES)].","finding":"","journal":"Annales medicales de Nancy","studyType":"Clinical Study"},{"pmid":"14446606","year":"1960","title":"[Study, in digestive pathology, of a new spasmolytic drug with predominatly musculotropic action: dihydrochloride of di-dipiproverine (L.D. 935)].","finding":"","journal":"La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris","studyType":"Clinical Study"},{"pmid":"13801296","year":"1959","title":"[Clinical study of an antispasmodic with a predominantly musculotropic action: 2-piperidinoethyl alpha-phenyl-alpha-piperidinoacetate dihydrochloride (dipiproverine hydrochloride)].","finding":"","journal":"Therapie","studyType":"Clinical Study"}],"tags":[{"label":"dipiproverine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["dipiproverine hydrochloride","dipiproverine HCl","LD 935","dipiproverine"],"offLabel":[],"synonyms":["dipiproverine hydrochloride","dipiproverine HCl","LD 935","dipiproverine"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"dipiproverine","explanation":"Imagine your bladder is like a balloon filling up with water. When the balloon gets too full, it can't hold any more water, and you need to urinate. Dipiproverine helps relax the muscles around the balloon, making it easier to empty and improving urine flow.","oneSentence":"Dipiproverine works by relaxing smooth muscle in the bladder neck and prostate, improving urine flow.","technicalDetail":"Dipiproverine exerts its effects by acting as a smooth muscle relaxant, specifically targeting the alpha-adrenergic receptors in the bladder neck and prostate, thereby increasing the bladder capacity and improving the urinary flow."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3737","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIPIPROVERINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:46:46.631826","biosimilars":[],"competitors":[],"genericName":"dipiproverine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"4XV7PTW3FZ","CHEBI":"CHEBI:135411","INN_ID":"866","UMLSCUI":"C1880344","ChEMBL_ID":"CHEMBL2110899","PUBCHEM_CID":"72072"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":3,"therapeuticAreas":["Urology"],"biosimilarFilings":[],"recentPublications":[{"date":"1964 Jun-Jul","pmid":"14205397","title":"[THE USE OF DIPIPROVERINE DURING THE VICHY THERMAL CURE IN THE TREATMENT OF BILIARY DYSKINESIA AND SPASMODIC COLOPATHIES. (DOCUMENTARY AND STATISTICAL STUDY APROPOS OF 98 CASES)].","journal":"Annales medicales de Nancy"},{"date":"1960 Feb 28","pmid":"14446606","title":"[Study, in digestive pathology, of a new spasmolytic drug with predominatly musculotropic action: dihydrochloride of di-dipiproverine (L.D. 935)].","journal":"La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris"},{"date":"1959","pmid":"13801296","title":"[Clinical study of an antispasmodic with a predominantly musculotropic action: 2-piperidinoethyl alpha-phenyl-alpha-piperidinoacetate dihydrochloride (dipiproverine hydrochloride)].","journal":"Therapie"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"DIPIPROVERINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Dipiproverine is a small molecule drug belonging to the dipiproverine class, originally developed by an unknown entity. Its current owner is also unknown. The exact target of dipiproverine is not specified, but it is used to treat certain conditions. The commercial status of dipiproverine is unclear, with unknown patent status and generic manufacturers. Key safety considerations are not well-documented.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}