{"id":"diphenhydramine-ampule","safety":{"commonSideEffects":[{"rate":"10-30%","effect":"Drowsiness"},{"rate":"5-20%","effect":"Dry mouth"},{"rate":"5-15%","effect":"Dizziness"}]},"_chembl":{"chemblId":"CHEMBL657","moleculeType":"Small molecule","molecularWeight":"255.36"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It works by competitively inhibiting the histamine H1 receptor, thereby reducing the symptoms of an allergic reaction. This results in decreased vasodilation, decreased vascular permeability, and decreased smooth muscle contraction.","oneSentence":"Diphenhydramine acts as an antihistamine by blocking the action of histamine in the body.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:45:51.163Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relief of allergy symptoms such as itching, redness, and swelling"}]},"trialDetails":[{"nctId":"NCT04270409","phase":"PHASE3","title":"Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma","status":"ACTIVE_NOT_RECRUITING","sponsor":"Sanofi","startDate":"2020-06-16","conditions":"Plasma Cell Myeloma","enrollment":337},{"nctId":"NCT05648058","phase":"PHASE3","title":"Role of Nefopam in Rituximab Transfusion Reaction","status":"UNKNOWN","sponsor":"Ministry Of Health / Nineveh Health Directorate","startDate":"2022-12-20","conditions":"Nefopam","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Allermine"],"phase":"phase_3","status":"active","brandName":"diphenhydramine ampule","genericName":"diphenhydramine ampule","companyName":"Ministry Of Health / Nineveh Health Directorate","companyId":"ministry-of-health-nineveh-health-directorate","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Diphenhydramine acts as an antihistamine by blocking the action of histamine in the body. Used for Relief of allergy symptoms such as itching, redness, and swelling.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}