{"id":"diphenan","rwe":[{"pmid":"13196028","year":"1954","title":"[Quantitative determination of diphenan and urethane].","finding":"","journal":"Svensk farmaceutisk tidskrift","studyType":"Clinical Study"},{"pmid":"13073294","year":"1953","title":"Treatment of enterobiasis (pinworm infestation) with diphenan, egression and gentian violet.","finding":"","journal":"Pediatrics","studyType":"Clinical Study"},{"pmid":"13045525","year":"1953","title":"Treatment of oxyuriasis with diphenan.","finding":"","journal":"Lancet (London, England)","studyType":"Clinical Study"},{"pmid":"15411617","year":"1950","title":"Diphenan in the treatment of enterobiasis.","finding":"","journal":"Canadian journal of public health = Revue canadienne de sante publique","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"difenan","offLabel":[],"synonyms":["diphenan","difenan","diphenane","carbaurine","carphenol","parabencil","p-Benzylphenyl carbamate"],"timeline":[],"approvals":[],"brandName":"Difenan","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine Difenan as a key that fits into a lock in the body. When it binds to its target, it helps to turn off or turn on certain processes that are involved in the disease it's meant to treat. This can help to restore balance and reduce symptoms.","oneSentence":"Difenan is a small molecule that works by binding to a specific target in the body to produce its therapeutic effect.","technicalDetail":"Difenan's mechanism of action is not well understood, but it is thought to involve binding to a specific protein or receptor in the body, which triggers a cascade of downstream effects that ultimately lead to its therapeutic effect."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3736","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIPHENAN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:41:03.497222","biosimilars":[],"competitors":[],"genericName":"diphenan","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"U129BBY8DB","CHEBI":"CHEBI:134933","INN_ID":"48","UMLSCUI":"C1880342","ChEMBL_ID":"CHEMBL608856","PUBCHEM_CID":"7572"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1954 Aug 20","pmid":"13196028","title":"[Quantitative determination of diphenan and urethane].","journal":"Svensk farmaceutisk tidskrift"},{"date":"1953 Jun","pmid":"13073294","title":"Treatment of enterobiasis (pinworm infestation) with diphenan, egression and gentian violet.","journal":"Pediatrics"},{"date":"1953 May 30","pmid":"13045525","title":"Treatment of oxyuriasis with diphenan.","journal":"Lancet (London, England)"},{"date":"1950 Apr","pmid":"15411617","title":"Diphenan in the treatment of enterobiasis.","journal":"Canadian journal of public health = Revue canadienne de sante publique"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Difenan (DIPHENAN) is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it is not known if it is FDA approved or off-patent. The approved indications for Difenan are also unknown. Further information on its pharmacokinetics, such as half-life and bioavailability, is not available. As a result, key safety considerations and generic manufacturers are also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}