{"id":"diperodon","rwe":[],"tags":[{"label":"diperodon","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Sodium channel alpha subunits; brain (Types I, II, III)","category":"target"},{"label":"SCN1A","category":"gene"},{"label":"SCN2A","category":"gene"},{"label":"SCN3A","category":"gene"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["diperodon hydrochloride","diothane hydrochloride","diperodon","diperodon HCl","diothane HCl"],"offLabel":[],"synonyms":["diperodon hydrochloride","diothane hydrochloride","diperodon","diperodon HCl","diothane HCl"],"timeline":[],"aiSummary":"Diperodon is a small molecule drug that targets sodium channel alpha subunits in the brain, specifically types I, II, and III. It is classified as a diperodon, but its commercial status and approved indications are unknown. As a small molecule, diperodon works by interacting with specific proteins in the brain to modulate sodium channel activity. The exact mechanism of action and key safety considerations are not well-documented. Further research is needed to fully understand the potential benefits and risks of this drug.","approvals":[],"ecosystem":[],"mechanism":{"target":"Sodium channel alpha subunits; brain (Types I, II, III)","targets":[{"gene":"SCN1A","source":"DrugCentral","target":"Sodium channel alpha subunits; brain (Types I, II, III)","protein":"Sodium channel protein type 1 subunit alpha"},{"gene":"SCN2A","source":"DrugCentral","target":"Sodium channel alpha subunits; brain (Types I, II, III)","protein":"Sodium channel protein type 2 subunit alpha"},{"gene":"SCN3A","source":"DrugCentral","target":"Sodium channel alpha subunits; brain (Types I, II, III)","protein":"Sodium channel protein type 3 subunit alpha"}],"modality":"Small Molecule","drugClass":"diperodon","explanation":"Imagine your brain cells are like a row of houses with electrical wires. Sodium channels are like the electrical outlets that let electricity flow in and out of the houses. Diperodon blocks these outlets, reducing the flow of electricity and helping to calm down abnormal electrical activity in the brain.","oneSentence":"Diperodon works by blocking sodium channels in the brain to reduce abnormal electrical activity.","technicalDetail":"Diperodon selectively binds to sodium channel alpha subunits, specifically types I, II, and III, to inhibit sodium influx and modulate neuronal excitability."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3734","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIPERODON","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:45:45.438320","biosimilars":[],"competitors":[{"drugName":"articaine","drugSlug":"articaine","fdaApproval":"2000-04-03","patentExpiry":"Mar 27, 2039","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"bepridil","drugSlug":"bepridil","fdaApproval":"1990-12-28","patentStatus":"Unknown","relationship":"same-target"},{"drugName":"brompheniramine","drugSlug":"brompheniramine","fdaApproval":"1957-08-23","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"butacaine","drugSlug":"butacaine","fdaApproval":"","relationship":"same-target"},{"drugName":"chlorphenamine","drugSlug":"chlorphenamine","fdaApproval":"1950-08-15","relationship":"same-target"},{"drugName":"chlorpromazine","drugSlug":"chlorpromazine","fdaApproval":"1957-09-18","patentStatus":"Unknown","relationship":"same-target"},{"drugName":"cinchocaine","drugSlug":"cinchocaine","fdaApproval":"","relationship":"same-target"},{"drugName":"cyproheptadine","drugSlug":"cyproheptadine","fdaApproval":"1961-10-17","genericCount":31,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"desipramine","drugSlug":"desipramine","fdaApproval":"1964-11-20","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"dicycloverine","drugSlug":"dicycloverine","fdaApproval":"1950-05-11","relationship":"same-target"}],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"diperodon","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"articaine","brandName":"articaine","genericName":"articaine","approvalYear":"2000","relationship":"same-target"},{"drugId":"bepridil","brandName":"bepridil","genericName":"bepridil","approvalYear":"1990","relationship":"same-target"},{"drugId":"brompheniramine","brandName":"brompheniramine","genericName":"brompheniramine","approvalYear":"1957","relationship":"same-target"},{"drugId":"butacaine","brandName":"butacaine","genericName":"butacaine","approvalYear":"","relationship":"same-target"},{"drugId":"chlorphenamine","brandName":"chlorphenamine","genericName":"chlorphenamine","approvalYear":"1950","relationship":"same-target"},{"drugId":"chlorpromazine","brandName":"chlorpromazine","genericName":"chlorpromazine","approvalYear":"1957","relationship":"same-target"},{"drugId":"cinchocaine","brandName":"cinchocaine","genericName":"cinchocaine","approvalYear":"","relationship":"same-target"},{"drugId":"cyproheptadine","brandName":"cyproheptadine","genericName":"cyproheptadine","approvalYear":"1961","relationship":"same-target"},{"drugId":"desipramine","brandName":"desipramine","genericName":"desipramine","approvalYear":"1964","relationship":"same-target"},{"drugId":"dicycloverine","brandName":"dicycloverine","genericName":"dicycloverine","approvalYear":"1950","relationship":"same-target"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"NUI":"N0000147184","MMSL":"4610","NDDF":"001364","UNII":"5YZ5R8I73Y","VUID":"4018890","CHEBI":"CHEBI:93842","VANDF":"4018890","RXNORM":"133043","UMLSCUI":"C0163518","ChEMBL_ID":"CHEMBL338667","DRUGBANK_ID":"DB11513","PDB_CHEM_ID":" POW","PUBCHEM_CID":"10831","SNOMEDCT_US":"373495000","MESH_SUPPLEMENTAL_RECORD_UI":"C027013"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":11,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"DIPERODON","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}