{"id":"dioxaphetyl-butyrate","rwe":[{"pmid":"41906200","year":"2026","title":"Preoperative Beta-Hydroxy-Beta-Methyl-Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice.","finding":"","journal":"Acta physiologica (Oxford, England)","studyType":"Clinical Study"},{"pmid":"41903849","year":"2026","title":"Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowel syndrome.","finding":"","journal":"Clinical nutrition ESPEN","studyType":"Clinical Study"},{"pmid":"41903401","year":"2026","title":"Short-chain fatty acids, neuroinflammation, and autism spectrum disorders: A mechanistic systematic review.","finding":"","journal":"Journal of neuroimmunology","studyType":"Clinical Study"},{"pmid":"41901189","year":"2026","title":"Combined Effects of Withaferin A and Sodium Butyrate on NF-κB Signaling and Epigenetic Regulation in Breast Cancer Cells.","finding":"","journal":"Nutrients","studyType":"Clinical Study"},{"pmid":"41901118","year":"2026","title":"Severity of Hypoxia-Induced Effects on 3T3-L1 Adipocyte Secretory Function Is Attenuated Dose-Dependently by Individual Short-Chain Fatty Acids.","finding":"","journal":"Nutrients","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"amidalgon","offLabel":[],"synonyms":["dioxaphetyl butyrate","spasmoxal","amidalgon","spasmoxale"],"timeline":[],"approvals":[],"brandName":"Amidalgon","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a complex orchestra, with many different instruments working together to create a harmonious whole. Amidalgon is like a new instrument that's been added to the orchestra, but we don't yet know how it fits in or what it does. As researchers learn more about how it works, they may be able to use it to help treat certain diseases or conditions.","oneSentence":"Amidalgon is thought to work by interacting with specific biological pathways, but the exact mechanism is unknown.","technicalDetail":"Amidalgon's mechanism of action is currently unknown, but it is likely to involve interaction with specific molecular targets, such as enzymes, receptors, or other proteins, to produce its therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3733","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIOXAPHETYL BUTYRATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:45:28.450715","biosimilars":[],"competitors":[],"genericName":"dioxaphetyl butyrate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"G751H98FY4","CHEBI":"CHEBI:135489","INN_ID":"611","UMLSCUI":"C1880340","ChEMBL_ID":"CHEMBL2106284","DRUGBANK_ID":"DB01475","PUBCHEM_CID":"222492"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":21582,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 May","pmid":"41906200","title":"Preoperative Beta-Hydroxy-Beta-Methyl-Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice.","journal":"Acta physiologica (Oxford, England)"},{"date":"2026 Mar 26","pmid":"41903849","title":"Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowel syndrome.","journal":"Clinical nutrition ESPEN"},{"date":"2026 Mar 24","pmid":"41903401","title":"Short-chain fatty acids, neuroinflammation, and autism spectrum disorders: A mechanistic systematic review.","journal":"Journal of neuroimmunology"},{"date":"2026 Mar 23","pmid":"41901189","title":"Combined Effects of Withaferin A and Sodium Butyrate on NF-κB Signaling and Epigenetic Regulation in Breast Cancer Cells.","journal":"Nutrients"},{"date":"2026 Mar 17","pmid":"41901118","title":"Severity of Hypoxia-Induced Effects on 3T3-L1 Adipocyte Secretory Function Is Attenuated Dose-Dependently by Individual Short-Chain Fatty Acids.","journal":"Nutrients"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Amidalgon, also known as DIOXAPHETYL BUTYRATE, is a small molecule compound with unknown target and drug class. Its commercial status and approved indications are currently unavailable. As a small molecule, it is likely to interact with specific biological pathways, but the exact mechanism of action is unknown. Further research is needed to determine its potential therapeutic applications and safety profile. The compound's pharmacokinetic properties, such as half-life and bioavailability, are also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}