{"id":"diisopromine","rwe":[{"pmid":"40712231","year":"2025","title":"Diisopromine as a non-labelled CYP3A4 substrate: Implications for breath test development.","finding":"","journal":"Bioorganic chemistry","studyType":"Clinical Study"}],"tags":[{"label":"diisopromine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A03AX02","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["diisopromine"],"offLabel":[],"synonyms":["diisopromine"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"diisopromine","explanation":"Unfortunately, we don't know how DIISOPROMINE works, but it's likely that it binds to a specific protein or receptor in the body, triggering a response that helps to treat a particular condition. This process is complex and involves many different molecules and cells working together. More research is needed to fully understand how DIISOPROMINE works.","oneSentence":"DIISOPROMINE works by interacting with a specific target in the body, but its exact mechanism is unknown.","technicalDetail":"The technical details of DIISOPROMINE's mechanism of action are unknown, but it is likely a reversible inhibitor of a specific enzyme or receptor, leading to a cascade of downstream effects that result in its therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/892","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIISOPROMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:37:38.145175","biosimilars":[],"competitors":[{"drugName":"isometheptene","drugSlug":"isometheptene","fdaApproval":"","relationship":"same-class"}],"genericName":"diisopromine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"isometheptene","brandName":"isometheptene","genericName":"isometheptene","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005402","UNII":"2825S6AW9U","INN_ID":"989","RXNORM":"236206","UMLSCUI":"C0771458","ChEMBL_ID":"CHEMBL2110849","KEGG_DRUG":"D07092","DRUGBANK_ID":"DB13476","PUBCHEM_CID":"22262"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"A03AX02","allCodes":["A03AX02"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025 Aug","pmid":"40712231","title":"Diisopromine as a non-labelled CYP3A4 substrate: Implications for breath test development.","journal":"Bioorganic chemistry"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"DIISOPROMINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"DIISOPROMINE is a small molecule drug in the diisopromine class, but its target and mechanism of action are unknown. Its commercial status and approved indications are also unclear. As a result, there is limited information available on its safety profile, pharmacokinetics, and generic availability. Further research is needed to fully understand this compound. Its development history is also unclear.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}