{"id":"diiodotyrosine","rwe":[{"pmid":"39633222","year":"2025","title":"Infrared Spectral Patterns of Thyroglobulin Bearing Thyroiditogenic Epitopes.","finding":"","journal":"The protein journal","studyType":"Clinical Study"},{"pmid":"39442452","year":"2024","title":"Identification and determination of the urinary metabolite of iodotyrosine invivo.","finding":"","journal":"Biochemical and biophysical research communications","studyType":"Clinical Study"},{"pmid":"39322975","year":"2024","title":"Reactivity, Pathways, and Iodinated Disinfection Byproduct Formation during Chlorination of Iodotyrosines Derived from Edible Seaweed.","finding":"","journal":"Environmental science & technology","studyType":"Clinical Study"},{"pmid":"38661522","year":"2024","title":"Identification of Iodotyrosines as Novel Substrates for the Thyroid Hormone Transporter MCT8.","finding":"","journal":"Thyroid : official journal of the American Thyroid Association","studyType":"Clinical Study"},{"pmid":"33760541","year":"2026","title":"Hyperthyroidism (Nursing).","finding":"","journal":"","studyType":"Clinical Study"}],"tags":[{"label":"diiodotyrosine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"H03BX01","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"cemiod","offLabel":[],"synonyms":["L-3,5-diiodotyrosine","agontan","apothyrin","cemiod","DL-3,5-Diiodotyrosine","dityrin","iodogorgoic acid","iodogorgonic acid","jodgorgon","diiodotyrosine"],"timeline":[],"approvals":[],"brandName":"Cemiod","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"diiodotyrosine","explanation":"Think of it like a puzzle piece - diiodotyrosine is a crucial part of the process that helps the thyroid gland make hormones that regulate our metabolism and energy levels. By providing this puzzle piece, Cemiod may help support the thyroid gland's function. However, more research is needed to fully understand how it works and its potential benefits and risks.","oneSentence":"Cemiod is thought to work by providing the body with a source of diiodotyrosine, a molecule that plays a role in the production of thyroid hormones.","technicalDetail":"Pharmacologically, diiodotyrosine is a precursor to triiodothyronine (T3) and thyroxine (T4), which are thyroid hormones produced by the thyroid gland. The exact mechanism of action of Cemiod is unclear, but it may involve increasing the availability of diiodotyrosine for thyroid hormone synthesis."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3146","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=diiodotyrosine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:43:06.437477","biosimilars":[],"competitors":[],"genericName":"diiodotyrosine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"007143","UNII":"6L57Q44ZWW","CHEBI":"CHEBI:15768","UMLSCUI":"C0012344","ChEMBL_ID":"CHEMBL1236469","DRUGBANK_ID":"DB03374","PDB_CHEM_ID":"TYI","PUBCHEM_CID":"9305","SNOMEDCT_US":"80393001","MESH_DESCRIPTOR_UI":"D004105"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":604,"therapeuticAreas":["Metabolic"],"atcClassification":{"source":"DrugCentral","atcCode":"H03BX01","allCodes":["H03BX01"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025 Feb","pmid":"39633222","title":"Infrared Spectral Patterns of Thyroglobulin Bearing Thyroiditogenic Epitopes.","journal":"The protein journal"},{"date":"2024 Nov 26","pmid":"39442452","title":"Identification and determination of the urinary metabolite of iodotyrosine invivo.","journal":"Biochemical and biophysical research communications"},{"date":"2024 Oct 8","pmid":"39322975","title":"Reactivity, Pathways, and Iodinated Disinfection Byproduct Formation during Chlorination of Iodotyrosines Derived from Edible Seaweed.","journal":"Environmental science & technology"},{"date":"2024 Jul","pmid":"38661522","title":"Identification of Iodotyrosines as Novel Substrates for the Thyroid Hormone Transporter MCT8.","journal":"Thyroid : official journal of the American Thyroid Association"},{"date":"2026 Jan","pmid":"33760541","title":"Hyperthyroidism (Nursing).","journal":""}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Cemiod, also known as diiodotyrosine, is a small molecule drug of the diiodotyrosine class. However, there is limited information available on this compound, and it does not appear to be a well-known or widely used medication. As a result, there is no clear information on its target, approved indications, or commercial status. Further research is needed to determine the potential uses and safety profile of Cemiod. Unfortunately, the available data is insufficient to provide a comprehensive summary.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}