{"id":"dihydroemetine","rwe":[],"tags":[{"label":"dihydroemetine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P01AX09","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"mebadin","offLabel":[],"synonyms":["dehydroemetine","mebadin","dihydroemetine"],"timeline":[],"approvals":[],"brandName":"Mebadin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"dihydroemetine","explanation":"Imagine your body as a city with a strong immune system that can fight off invaders. Mebadin is like a special kind of police officer that helps your immune system catch and eliminate the bad guys, in this case, parasites. By stopping the parasites from growing and multiplying, Mebadin helps your body recover from infection.","oneSentence":"Mebadin works by inhibiting the growth and replication of certain parasites.","technicalDetail":"Dihydroemetine is a derivative of emetine, a natural product with antiprotozoal activity. It is thought to work by inhibiting protein synthesis in the parasite, ultimately leading to cell death."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3129","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=dihydroemetine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:36:39.774984","biosimilars":[],"competitors":[{"drugName":"atovaquone","drugSlug":"atovaquone","fdaApproval":"1992-11-25","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"trimetrexate","drugSlug":"trimetrexate","fdaApproval":"1993-12-17","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"nitazoxanide","drugSlug":"nitazoxanide","fdaApproval":"2002-11-22","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"dihydroemetine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"atovaquone","brandName":"atovaquone","genericName":"atovaquone","approvalYear":"1992","relationship":"same-class"},{"drugId":"trimetrexate","brandName":"trimetrexate","genericName":"trimetrexate","approvalYear":"1993","relationship":"same-class"},{"drugId":"nitazoxanide","brandName":"nitazoxanide","genericName":"nitazoxanide","approvalYear":"2002","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006030","UNII":"7S79QT1T91","CHEBI":"CHEBI:149634","INN_ID":"1796","RXNORM":"3142","UMLSCUI":"C0082286","ChEMBL_ID":"CHEMBL547470","KEGG_DRUG":"D00828","DRUGBANK_ID":"DB13865","PUBCHEM_CID":"21022","MESH_SUPPLEMENTAL_RECORD_UI":"C086742"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Immunology"],"atcClassification":{"source":"DrugCentral","atcCode":"P01AX09","allCodes":["P01AX09"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Mebadin (dihydroemetine) is a small molecule drug in the dihydroemetine class, but specific details about its development, commercial status, and approved indications are not available. As a dihydroemetine, it is likely used to treat certain parasitic infections. However, without further information, it is difficult to provide a comprehensive summary. Further research is needed to determine its target, pharmacokinetic properties, and safety considerations. It is unclear whether Mebadin is patented or available as a generic product.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}