{"id":"dihexyverine","rwe":[{"pmid":"14251293","year":"1964","title":"[MECHANISM OF THE PHENOMENA OF SYNERGISM OF EXPERIMENTAL SLEEP. I. STUDY OF THE ASSOCIATIONS CHLORPROMAZINE-HEXOBARBITOL, DIHEXYVERINE-HEXOBARBITAL, IN MICE].","finding":"","journal":"Archives des sciences physiologiques","studyType":"Clinical Study"},{"pmid":"13944939","year":"1962","title":"[Preliminary clinical study on the use of dihexyverine in obstetrics].","finding":"","journal":"Canadian Medical Association journal","studyType":"Clinical Study"},{"pmid":"13892604","year":"1962","title":"[Preliminary clinical study on the use of dihexyverine in obstetrics].","finding":"","journal":"L'union medicale du Canada","studyType":"Clinical Study"},{"pmid":"13885120","year":"1962","title":"[Clinical experimentation with an antispasmodic, \"Dihexyverine\", in obstetrical practice].","finding":"","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille","studyType":"Clinical Study"},{"pmid":"13511938","year":"1958","title":"[Experimental study on the use of dihexyverine in obstetrical labor by the physiological accelerated labor method].","finding":"","journal":"Concours medical","studyType":"Clinical Study"}],"tags":[{"label":"dihexyverine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A03AA08","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"dihexyverin","offLabel":[],"synonyms":["dihexyverine","dihexiverine","dihexyverin"],"timeline":[],"approvals":[],"brandName":"Dihexyverin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"dihexyverine","explanation":"Imagine your muscles are like rubber bands - when they contract, they get shorter and tighter. Dihexyverine is believed to help relax these muscles, making them less tight and less likely to cause problems. This can be helpful in treating conditions where muscle spasms or contractions are a concern.","oneSentence":"Dihexyverine is thought to work by inhibiting smooth muscle contraction, although the exact mechanism is unclear.","technicalDetail":"Dihexyverine is a smooth muscle relaxant that may exert its effects by blocking calcium channels or inhibiting the release of calcium ions, leading to reduced muscle contraction and relaxation of smooth muscle tissue."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/883","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIHEXYVERINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:42:15.743506","biosimilars":[],"competitors":[{"drugName":"oxyphencyclimine","drugSlug":"oxyphencyclimine","fdaApproval":"","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"dicycloverine","drugSlug":"dicycloverine","fdaApproval":"1950-05-11","relationship":"same-class"}],"genericName":"dihexyverine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"oxyphencyclimine","brandName":"oxyphencyclimine","genericName":"oxyphencyclimine","approvalYear":"","relationship":"same-class"},{"drugId":"dicycloverine","brandName":"dicycloverine","genericName":"dicycloverine","approvalYear":"1950","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005406","UNII":"J2FQ66RU9W","CHEBI":"CHEBI:135367","INN_ID":"361","RXNORM":"236209","UMLSCUI":"C0771461","ChEMBL_ID":"CHEMBL2110912","KEGG_DRUG":"D07821","DRUGBANK_ID":"DB13678","PUBCHEM_CID":"21788"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":12,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"A03AA08","allCodes":["A03AA08"]},"biosimilarFilings":[],"recentPublications":[{"date":"1964","pmid":"14251293","title":"[MECHANISM OF THE PHENOMENA OF SYNERGISM OF EXPERIMENTAL SLEEP. I. STUDY OF THE ASSOCIATIONS CHLORPROMAZINE-HEXOBARBITOL, DIHEXYVERINE-HEXOBARBITAL, IN MICE].","journal":"Archives des sciences physiologiques"},{"date":"1962 Nov 24","pmid":"13944939","title":"[Preliminary clinical study on the use of dihexyverine in obstetrics].","journal":"Canadian Medical Association journal"},{"date":"1962 Aug","pmid":"13892604","title":"[Preliminary clinical study on the use of dihexyverine in obstetrics].","journal":"L'union medicale du Canada"},{"date":"1962 Feb","pmid":"13885120","title":"[Clinical experimentation with an antispasmodic, \"Dihexyverine\", in obstetrical practice].","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille"},{"date":"1958 Mar 8","pmid":"13511938","title":"[Experimental study on the use of dihexyverine in obstetrical labor by the physiological accelerated labor method].","journal":"Concours medical"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Dihexyverine is a small molecule drug in the dihexyverine class, but specific details about its target, pharmacokinetics, and commercial status are unknown. Its mechanism of action and approved indications are also unclear. As a result, there is limited information available about this compound. Further research is needed to understand its potential therapeutic applications and safety profile. Its current status and development stage are also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}