{"id":"difflam-forte","safety":{"commonSideEffects":[{"rate":null,"effect":"Local irritation or burning sensation"},{"rate":null,"effect":"Allergic reactions (rare)"},{"rate":null,"effect":"Numbness or tingling"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Difflam Forte contains benzydamine hydrochloride, a non-steroidal anti-inflammatory drug (NSAID) that works locally in the mouth and throat to inhibit prostaglandin synthesis and reduce inflammatory mediators. It provides analgesic and anti-inflammatory effects without systemic absorption, making it suitable for topical oral use.","oneSentence":"Difflam Forte is a topical anti-inflammatory agent that reduces inflammation and pain in the oral cavity and throat.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:44:43.721Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Oral inflammation and pain (pharyngitis, stomatitis, mouth ulcers)"},{"name":"Post-operative oral and throat pain"}]},"trialDetails":[{"nctId":"NCT02608788","phase":"PHASE4","title":"S.L. Spray Solution® and Difflam® and Acular®Spray for the Prevention of Postoperative Sore Throat","status":"COMPLETED","sponsor":"Chang Gung Memorial Hospital","startDate":"2014-09","conditions":"Sore Throat","enrollment":380}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Tantum Verde®"],"phase":"marketed","status":"active","brandName":"Difflam Forte ®","genericName":"Difflam Forte ®","companyName":"Chang Gung Memorial Hospital","companyId":"chang-gung-memorial-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Difflam Forte is a topical anti-inflammatory agent that reduces inflammation and pain in the oral cavity and throat. Used for Oral inflammation and pain (pharyngitis, stomatitis, mouth ulcers), Post-operative oral and throat pain.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}