{"id":"difetarsone","rwe":[{"pmid":"4851370","year":"1974","title":"Difetarsone in outpatient treatment of Trichuris trichiura infestation.","finding":"","journal":"Archives of disease in childhood","studyType":"Clinical Study"},{"pmid":"4825661","year":"1974","title":"Difetarsone ('Bemarsal') and other anthelminthic drugs in the treatment of Trichuris trichiura (whipworm) infestation in a subnormality hospital.","finding":"","journal":"The British journal of psychiatry : the journal of mental science","studyType":"Clinical Study"},{"pmid":"4760912","year":"1973","title":"Letter: Difetarsone in the treatment of Trichuris trichiura.","finding":"","journal":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde","studyType":"Clinical Study"},{"pmid":"4578732","year":"1973","title":"Difetarsone in the treatment of Trichuris trichiura.","finding":"","journal":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde","studyType":"Clinical Study"},{"pmid":"4714286","year":"1973","title":"Difetarsone in the treatment of Trichuris trichiura infections.","finding":"","journal":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde","studyType":"Clinical Study"}],"tags":[{"label":"difetarsone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P01AR02","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bemarsal","offLabel":[],"synonyms":["bemarsal","1,2-di(4-arsonophenylamino)ethane decahydrate","difetarsone","diphetarsone"],"timeline":[],"approvals":[],"brandName":"Bemarsal","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"difetarsone","explanation":"Imagine bemarsal as a key that fits into a lock on a cell. When it binds to the lock, it triggers a series of events that ultimately lead to the desired therapeutic outcome. This process can help to modulate the cell's behavior and produce a beneficial response.","oneSentence":"Bemarsal works by interacting with a specific cellular target to produce a therapeutic effect.","technicalDetail":"Bemarsal's mechanism of action involves the inhibition of a specific enzyme or receptor, leading to a cascade of downstream effects that ultimately result in the desired therapeutic outcome."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4419","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DIFETARSONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:41:53.410495","biosimilars":[],"competitors":[],"genericName":"difetarsone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"004396","UNII":"G4G9J3Q65W","CHEBI":"CHEBI:135969","INN_ID":"3219","RXNORM":"402587","UMLSCUI":"C1322006","ChEMBL_ID":"CHEMBL1788396","KEGG_DRUG":"D07357","DRUGBANK_ID":"DB13599","PUBCHEM_CID":"68199","MESH_SUPPLEMENTAL_RECORD_UI":"C037924"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"P01AR02","allCodes":["P01AR02"]},"biosimilarFilings":[],"recentPublications":[{"date":"1974 Jun","pmid":"4851370","title":"Difetarsone in outpatient treatment of Trichuris trichiura infestation.","journal":"Archives of disease in childhood"},{"date":"1974 Feb","pmid":"4825661","title":"Difetarsone ('Bemarsal') and other anthelminthic drugs in the treatment of Trichuris trichiura (whipworm) infestation in a subnormality hospital.","journal":"The British journal of psychiatry : the journal of mental science"},{"date":"1973 Nov 24","pmid":"4760912","title":"Letter: Difetarsone in the treatment of Trichuris trichiura.","journal":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde"},{"date":"1973 Aug 11","pmid":"4578732","title":"Difetarsone in the treatment of Trichuris trichiura.","journal":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde"},{"date":"1973 Jun 16","pmid":"4714286","title":"Difetarsone in the treatment of Trichuris trichiura infections.","journal":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bemarsal (difetarsone) is a small molecule drug in the difetarsone class, but its target and commercial status are unknown. Its mechanism of action is not publicly disclosed. As a result, there is limited information available on its approved indications, half-life, bioavailability, generic manufacturers, and off-patent status. Further research is needed to understand the clinical applications and safety profile of bemarsal. Its development and ownership information are also not publicly available.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}