{"id":"dichlorophenarsine","rwe":[{"pmid":"13690816","year":"1960","title":"A clinical trial of dichlorophenarsine hydrochloride in treatment of canine heartworm infection.","finding":"","journal":"Journal of the American Veterinary Medical Association","studyType":"Clinical Study"},{"pmid":"18910642","year":"1948","title":"Protective action of vitamins C and P against dichlorophenarsine hydrochloride.","finding":"","journal":"Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)","studyType":"Clinical Study"},{"pmid":"20289294","year":"1947","title":"Dichlorophenarsine hydrochloride in the treatment of syphilis.","finding":"","journal":"American journal of syphilis, gonorrhea, and venereal diseases","studyType":"Clinical Study"},{"pmid":"21020990","year":"1945","title":"[Syphilis treatment by dichlorophenarsine hydrochloride (chlorarsine)].","finding":"","journal":"Actas dermo-sifiliograficas","studyType":"Clinical Study"}],"tags":[{"label":"dichlorophenarsine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"dichloromapharsen","offLabel":[],"synonyms":["dichlorophenarsine","dichloromapharsen","dichloromapharside","dichlorophenarsine hydrochloride","dichlorophenarsine HCl"],"timeline":[],"approvals":[],"brandName":"Dichloromapharsen","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"dichlorophenarsine","explanation":"Imagine your cells are like a city with many different buildings and roads. Dichlorophenarsine is like a traffic jam that disrupts the normal flow of things, but we're not entirely sure how it does that or which roads it blocks. This can affect how cells work and communicate with each other.","oneSentence":"Dichlorophenarsine is thought to work by interfering with cellular processes, but the exact mechanism is not well understood.","technicalDetail":"Dichlorophenarsine is a small molecule that likely interacts with cellular targets, potentially disrupting protein function or altering cellular signaling pathways, but the specific molecular mechanisms remain unclear."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3728","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=dichlorophenarsine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:39:13.151020","biosimilars":[],"competitors":[],"genericName":"dichlorophenarsine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"3WD5400T9N","CHEBI":"CHEBI:135036","INN_ID":"1498","UMLSCUI":"C2699630","PUBCHEM_CID":"68302","SECONDARY_CAS_RN":"536-29-8"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1960 Dec 15","pmid":"13690816","title":"A clinical trial of dichlorophenarsine hydrochloride in treatment of canine heartworm infection.","journal":"Journal of the American Veterinary Medical Association"},{"date":"1948 Mar","pmid":"18910642","title":"Protective action of vitamins C and P against dichlorophenarsine hydrochloride.","journal":"Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)"},{"date":"1947 Mar","pmid":"20289294","title":"Dichlorophenarsine hydrochloride in the treatment of syphilis.","journal":"American journal of syphilis, gonorrhea, and venereal diseases"},{"date":"1945 Dec","pmid":"21020990","title":"[Syphilis treatment by dichlorophenarsine hydrochloride (chlorarsine)].","journal":"Actas dermo-sifiliograficas"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Dichloromapharsen (dichlorophenarsine) is a small molecule drug of the dichlorophenarsine class, but its target and exact mechanism of action are unknown. It is not FDA-approved for any indications. The commercial status of dichlorophenarsine is unclear, and it may be patented or off-patent. As a result, there is limited information available on its safety profile and pharmacokinetic properties. Further research is needed to fully understand the properties and potential uses of dichlorophenarsine.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}