{"id":"dhacm-amniowrap","safety":{"commonSideEffects":[{"rate":null,"effect":"Infection at graft site"},{"rate":null,"effect":"Graft rejection or failure to integrate"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"dHACM is a decellularized, dehydrated allograft derived from human amniotic and chorionic membranes that contains native extracellular matrix proteins, growth factors, and cytokines. When applied to wounds or surgical sites, it acts as a biological dressing and scaffold to promote epithelialization, reduce inflammation, and facilitate tissue repair. The graft is resorbed over time as native tissue regenerates.","oneSentence":"dHACM (dehydrated human amnion/chorion membrane) is a biologic tissue graft that provides a scaffold for wound healing and tissue regeneration through its extracellular matrix components.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:44:38.716Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Diabetic foot ulcers"},{"name":"Chronic wounds"},{"name":"Surgical wounds"},{"name":"Burn wounds"}]},"trialDetails":[{"nctId":"NCT04417140","phase":"PHASE4","title":"A Prospective, Double-Blinded, Randomized Controlled Trial of dHACM for Incisional Hernia Prophylaxis","status":"UNKNOWN","sponsor":"Louisiana State University Health Sciences Center in New Orleans","startDate":"2020-05-20","conditions":"Incisional Hernia","enrollment":533}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"dHACM (AmnioWrap)","genericName":"dHACM (AmnioWrap)","companyName":"Louisiana State University Health Sciences Center in New Orleans","companyId":"louisiana-state-university-health-sciences-center-in-new-orleans","modality":"Biologic","firstApprovalDate":"","aiSummary":"dHACM (dehydrated human amnion/chorion membrane) is a biologic tissue graft that provides a scaffold for wound healing and tissue regeneration through its extracellular matrix components. Used for Diabetic foot ulcers, Chronic wounds, Surgical wounds.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}